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Ligand N-benzyloxycarbonyl-3-aminopropanal Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 1 H1 3 NO3
N-benzyloxycarbonyl-3-aminopropanal
PQMOZOQTXKMYSK-UHFFFAOYSA-N
benzyl (3-oxopropyl)carbamate, N-Cbz-3-aminopropanal
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (6 results)
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D-alanine + benzyl (3-oxopropyl)carbamate + H2O = (3S)-N6-[(benzyloxy)carbonyl]-3-hydroxy-2-methyl-L-lysine + (2S,3R)-2-amino-6-[[(benzyloxy)carbonyl]amino]-3-hydroxy-2-methylhexanoic acid
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D-serine + benzyl (3-oxopropyl)carbamate + H2O = (3S)-N6-[(benzyloxy)carbonyl]-3-hydroxy-2-(hydroxymethyl)-L-lysine + (3R)-N6-[(benzyloxy)carbonyl]-3-hydroxy-2-(hydroxymethyl)-L-lysine
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glycine + benzyl (3-oxopropyl)carbamate + H2O = (2S,3S)-2-amino-6-[[(benzyloxy)carbonyl]amino]-3-hydroxyhexanoic acid + (2S,3R)-2-amino-6-[[(benzyloxy)carbonyl]amino]-3-hydroxyhexanoic acid
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N-benzyloxycarbonyl-3-aminopropanal + glycine = (2S,3R)-2-amino-5-(benzyloxycarbonylamino)-3-hydroxypentanoic acid
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N-benzyloxycarbonyl-3-aminopropanal + glycine = (2S,3S)-2-amino-5-(benzyloxycarbonylamino)-3-hydroxypentanoic acid
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benzyl (3-oxopropyl)carbamate + 2-oxopropanoate = (3R)-5-[[(benzyloxy)carbonyl]amino]-3-hydroxypentanoate + (3S)-5-[[(benzyloxy)carbonyl]amino]-3-hydroxypentanoate
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Product in Enzyme-catalyzed Reactions (2 results)
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N-Cbz-3-amino-1-propanol + H2O2 = N-Cbz-3-aminopropanal + H2O
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N-Cbz-3-amino-1-propanol + tert-butyl hydroperoxide = N-Cbz-3-aminopropanal + H2O + ?
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Enzyme Kinetic Parameters
References & Links Literature References (3)
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Serine hydroxymethyl transferase from Streptococcus thermophilus and L-threonine aldolase from Escherichia coli as stereocomplementary biocatalysts for the synthesis of beta-hydroxy-alpha,omega-diamino acid derivatives
2008
Gutierrez, M.L.; Garrabou, X.; Agosta, E.; Servi, S.; Parella, T.; Joglar, J.; Clapes, P.
Chemistry
14
4647-4656
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2-Keto-3-deoxy-L-rhamnonate aldolase (YfaU) as catalyst in aldol additions of pyruvate to amino aldehyde derivatives
2017
Hernandez, K.; Gomez, A.; Joglar, J.; Bujons, J.; Parella, T.; Clapes, P.
Adv. Synth. Catal.
359
2090-2100
Engineered L-serine hydroxymethyltransferase from Streptococcus thermophilus for the synthesis of alpha,alpha-dialkyl-alpha-amino acids
2015
Hernandez, K.; Zelen, I.; Petrillo, G.; Uson, I.; Wandtke, C.M.; Bujons, J.; Joglar, J.; Parella, T.; Clapes, P.
Angew. Chem. Int. Ed. Engl.
54
3013-3017
Links to other databases for N-benzyloxycarbonyl-3-aminopropanal