Ligand L-phenylglycine

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Basic Ligand Information

Molecular Structure
Picture of L-phenylglycine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H9NO2
L-phenylglycine
ZGUNAGUHMKGQNY-ZETCQYMHSA-N
Synonyms:
(2S)-amino(phenyl)ethanoic acid, (S)-2-aminophenylacetate, (S)-phenylglycine, DL-2-phenylglycine, L-2-phenylglycine, Phg

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-Phenylglycine + pyruvate + NADH = N-[1-(R)-(Carboxy)ethyl]-(S)-phenylglycine + NAD+
show the reaction diagram
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L-phenylglycine + 2-oxoglutarate = ? + L-glutamate
show the reaction diagram
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L-Phenylglycine + pyruvate = L-Ala + ? + CO2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-glutamate + phenylglyoxylate = L-phenylglycine + 2-oxoglutarate
show the reaction diagram
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phenylglyoxylate + L-phenylalanine = L-phenylglycine + phenylpyruvate
show the reaction diagram
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Phg-7-amido-4-methylcoumarin + H2O = Phg + 7-amino-4-methylcoumarin
show the reaction diagram
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(S)-2-aminophenylacetamide + H2O = (S)-2-aminophenylacetate + NH3
show the reaction diagram
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N-formyl-phenylglycine + H2O = (S)-phenylglycine + formate
show the reaction diagram
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N-glutaryl-L-phenylglycine + H2O = glutarate + L-phenylglycine
show the reaction diagram
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(R,S)-phenylglycinonitrile + H2O = (S)-phenylglycine + phenylglycine amide + NH3
show the reaction diagram
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amino(phenyl)propanedioic acid = (2S)-amino(phenyl)ethanoic acid + CO2
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
5 mM, 1.74fold activation
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive with L-Phe
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
13.6
-
at pH 7.5 and 30°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
28.3
-
pyruvate and NADH as cosubstrates
0.145
-
at pH 7.5 and 30°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
8.32
-
-

References & Links

Links to other databases for L-phenylglycine

ChEBI
PubChem
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PubChem