Ligand His-Pro

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Basic Ligand Information

Molecular Structure
Picture of His-Pro (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H16N4O3
His-Pro
CRNXHFXAXBWIRH-UHFFFAOYSA-M
Synonyms:
His-Pro-OH, L-His-L-Pro, L-histidyl-L-proline

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
His-Pro + H2O = His + Pro
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acid-thyroliberin + H2O = pyroglutamate + His-Pro
show the reaction diagram
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pyroglutamyl-His-Pro-OH + H2O = pyroglutamate + His-Pro-OH
show the reaction diagram
-
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ATP + histidine + proline = ADP + phosphate + L-histidyl-L-proline
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
-
16% inhibition at 1 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3000
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pH 7.5, 55°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for His-Pro

ChEBI
PubChem
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PubChem