Ligand 6-mercaptopurine riboside

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Basic Ligand Information

Molecular Structure
Picture of 6-mercaptopurine riboside (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H12N4O4S
6-mercaptopurine riboside
NKGPJODWTZCHGF-VTHZCTBJSA-N
Synonyms:
6-mercaptopurine-riboside, 6-mercaptopurine nucleoside, 6-thioinosine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-mercaptopurine riboside + O2 = riburonosyl-6-mercaptopurine + H2O2
show the reaction diagram
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6-mercaptopurine riboside + phosphate = alpha-D-ribose 1-phosphate + 6-mercaptopurine
show the reaction diagram
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6-mercaptopurine riboside + H2O = 6-mercaptopurine + D-ribose
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thio-IMP + H2O = 6-thioinosine + phosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10 mM, 30.0% inhibition
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Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.07
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-

References & Links

Links to other databases for 6-mercaptopurine riboside

ChEBI
PubChem
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PubChem