Ligand (S)-norreticuline

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Basic Ligand Information

Molecular Structure
Picture of (S)-norreticuline (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C18H21NO4
(S)-norreticuline
FVEMXQCEJGGXJB-AWEZNQCLSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2 = 1,2-dehydronorreticuline + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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S-Adenosylmethionine + (S)-norreticuline = S-Adenosylhomocysteine + (S)-scoulerine
show the reaction diagram
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S-adenosyl-L-methionine + (S)-norreticuline = S-adenosyl-L-homocysteine + norcodamine + norlaudanine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-Adenosyl-L-methionine + (S)-3'-hydroxy-coclaurine = S-Adenosyl-L-homocysteine + (S)-norreticuline
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition at 0.001 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.01
-
product norlaudanine, pH 8.4, 35°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0382
-
product norlaudanine, pH 8.4, 35°C

References & Links

Links to other databases for (S)-norreticuline

ChEBI
PubChem
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PubChem