Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.00017
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme N132A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.00082
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R95A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0009
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R116A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0015
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme N126A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.003
-
in 100 mM Tris (pH 8.0), 1 mM EDTA, 1 mM dithiothreitol, and 0.2 mg/ml bovine serum albumin, at 22°C
0.0035
-
His-tagged wild-type
0.0038
-
using the DNA sequence 5'-GCATACCCGATCAAGTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0038
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0055
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme K139A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.008
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme K139A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0083
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R95A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.013
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R116A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.015
-
20mer duplex, unligated, single-site, pH 8.0, 25°C
0.015
-
using the DNA sequence 5'-GCATAAAAGATCGTCTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.015
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.019
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R137A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.02
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme N132A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.058
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R137A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.00000000000001
-
His-tagged wild-type
0.00000000000002
-
mutant S124D
0.00000191
-
pH 7.8, 33°C
0.000007
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R116A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000008
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R95A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.00001
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme N132A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0000227
-
using the DNA sequence 5'-GCATACCCGATCAAGTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000023
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000027
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme K139A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000031
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme N126A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000035
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R116A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000044
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme K139A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000076
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme N132A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0000809
-
using the DNA sequence 5'-GCATAAAAGATCGTCTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000081
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', wild type enzyme, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000083
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R137A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.000086
-
using the preferred sequence 5'-GCATACCGGATCAAGTAAATG-3', mutant enzyme R95A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.00015
-
at pH 5.5 and 37°C
0.00022
-
using the non-preferred sequence 5'-GCATAAAAGATCGTCTAAATG-3', mutant enzyme R137A, in 20 mM potassium phosphate, pH 7.5, 200 mM NaCl, 0.2 mM EDTA, 0.2 mg/ml bovine serum albumin, 2 mM dithiothreitol, 10% (v/v) glycerol, at 22°C
0.0003
-
in 50 mM NaCl, 50 mM HEPES, 1 mM EDTA, pH 7.5, temperature not specified in the publication
0.0199
-
in 10 mM Tris/HCl, pH 8.0, 5 mM 2-mercaptoethanol, at 37°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REBASE: restriction enzymes and methyltransferases
2003
Roberts, R.J.; Vincze, T.; Posfai, J.; Macelis, D.
Nucleic Acids Res.
31
418-420
N6-Adenine DNA-methyltransferase in wheat seedlings
2002
Fedoreyeva, L.I.; Vanyushin, B.F.
FEBS Lett.
514
305-308
A dual role for substrate S-adenosyl-L-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase
2001
Malygin, E.G.; Evdokimov, A.A.; Zinoviev, V.V.; Ovechkina, L.G.; Lindstrom, W.M.; Reich, N.O.; Schlagman, S.L.; Hattman, S.
Nucleic Acids Res.
29
2361-2369
Phage T4 DNA [N6-adenine]methyltransferase. Overexpression, purification, and characterization
1995
Kossykh, V.G.; Schlagman, S.L.; Hattman, S.
J. Biol. Chem.
270
14389-14393
-
Single turnover kinetics of methylation by T4 DNA-(N6-adenine)-methyltransferase
2001
Malygin, E.G.; Ovechkina, L.G.; Evdokimov, A.A.; Zinoviev, V.V.
Mol. Biol.
35
56-68
Bacteriophage T4 Dam DNA-[N6-adenine]methyltransferase. Kinetic evidence for a catalytically essential conformational change in the ternary complex
2002
Evdokimov, A.A.; Zinoviev, V.V.; Malygin, E.G.; Schlagman, S.L.; Hattman, S.
J. Biol. Chem.
277
279-286
Pre-steady state kinetics of bacteriophage T4 Dam DNA-[N6-adenine] methyltransferase: interaction with native (GATC) or modified sites
2000
Malygin, E.G.; Lindstrom, W.M., Jr.; Schlagman, S.L.; Hattman, S.; Reich, N.O.
Nucleic Acids Res.
28
4207-4211
A cell cycle-regulated adenine DNA methyltransferase from Caulobacter crescentus processively methylates GANTC sites on hemimethylated DNA
1998
Berdis, A.J.; Lee, I.; Coward, J.K.; Stephens, C.; Wright, R.; Shapiro, L.; Benkovic, S.J.
Proc. Natl. Acad. Sci. USA
95
2874-2879
Dam methyltransferase from Escherichia coli. Kinetic studies using modified DNA oligomers. Nonmethylated substrates
1997
Thielking, V.; Du Bois, S.; Eritja, R.; Guschlbauer, W.
Biol. Chem.
378
407-415
Phage T4 DNA [N6-adenine] methyltransferase. Kinetic studies using oligonucleotides containing native or modified recognition sites
1998
Zinoviev, V.V.; Evdokimov, A.A.; Gorbunov, Y.A.; Malygin, E.G.; Kossykh, V.G.; Hattman, S.
Biol. Chem.
379
481-488
-
Interaction of T4 phage DNA-[N6-adenine]-methyltransferase with substrates containing defective recognition sites
1997
Petrov, N.A.; Gorbunov, Y.A.; Malygin, E.G.
Mol. Biol.
31
827-831
Biochemical characterization of VspI methyltransferase
1995
Degtyarev, S.K.; Prikhodko, E.A.; Rechkunova, N.I.; Prikhodko, G.G.; Krasnykh, V.N.
Gene
157
65-66
Comparative studies of the phage T2 and T4 DNA (N6-adenine)methyltransferases: amino acid changes that affect catalytic activity
1997
Kossykh, V.G.; Schlagman, S.L.; Hattman, S.
J. Bacteriol.
179
3239-3243
Dam methylase from Escherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates
1995
Marzabal, S.; DuBois, S.; Thielking, V.; Cano, A.; Eritja, R.; Guschlbauer, W.
Nucleic Acids Res.
23
3648-3655
On the substrate specificity of DNA methyltransferases. Adenine-N6 DNA methyltransferases also modify cytosine residues at position N4
1999
Jeltsch, A.; Christ, F.; Fatemi, M.; Roth, M.
J. Biol. Chem.
274
19538-19544
VspI methylase belongs to m6A-gamma class of adenine methylase
1993
Degtyarev, S.K.; Prikhodæko, E.A.; Prikhodæko, G.G.; Krasnykh, V.N.
Nucleic Acids Res.
21
2015
In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation
1985
Chetsanga, C.J.; Grigorian, C.
Proc. Natl. Acad. Sci. USA
82
633-637
Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase
2005
Horton, J.R.; Liebert, K.; Hattman, S.; Jeltsch, A.; Cheng, X.
Cell
121
349-361
Characterization of the DNA adenine 5'-GATC-3' methylase HpyIIIM from Helicobacter pylori
2004
Simala-Grant, J.L.; Lam, E.; Keelan, M.; Taylor, D.E.
Curr. Microbiol.
49
47-54
A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability
2004
Kossykh, V.G.; Lloyd, R.S.
J. Bacteriol.
186
2061-2067
DNA (cytosine-N4-)- and -(adenine-N6-)-methyltransferases have different kinetic mechanisms but the same reaction route. A comparison of M.BamHI and T4 Dam
2003
Malygin, E.G.; Zinoviev, V.V.; Evdokimov, A.A.; Lindstrom, W.M., Jr.; Reich, N.O.; Hattman, S.
J. Biol. Chem.
278
15713-15719
Structures of liganded and unliganded RsrI N6-adenine DNA methyltransferase: a distinct orientation for active cofactor binding
2003
Thomas, C.B.; Scavetta, R.D.; Gumport, R.I.; Churchill, M.E.
J. Biol. Chem.
278
26094-26101
Bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase): evidence for two distinct stages of methylation under single turnover conditions
2003
Malygin, E.G.; Lindstrom, W.M., Jr.; Zinoviev, V.V.; Evdokimov, A.A.; Schlagman, S.L.; Reich, N.O.; Hattman, S.
J. Biol. Chem.
278
41749-41755
Bacteriophage T4 Dam DNA-(N6-adenine)-methyltransferase. Processivity and orientation to the methylation target
2003
Zinoviev, V.V.; Evdokimov, A.A.; Malygin, E.G.; Schlagman, S.L.; Hattman, S.
J. Biol. Chem.
278
7829-7833
Kinetic and catalytic properties of dimeric KpnI DNA methyltransferase
2003
Bheemanaik, S.; Chandrashekaran, S.; Nagaraja, V.; Rao, D.N.
J. Biol. Chem.
278
7863-7874
Functional characterization of Escherichia coli DNA adenine methyltransferase, a novel target for antibiotics
2004
Mashhoon, N.; Carroll, M.; Pruss, C.; Eberhard, J.; Ishikawa, S.; Estabrook, R.A.; Reich, N.
J. Biol. Chem.
279
52075-52081
Stopped-flow and mutational analysis of base flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase
2004
Liebert, K.; Hermann, A.; Schlickenrieder, M.; Jeltsch, A.
J. Mol. Biol.
341
443-454
-
Molecular enzymology of phage T4 Dam DNA methyltransferase
2004
Zinoviev, V.V.; Evdokimov, A.A.; Hattman, S.; Malygin, E.G.
Mol. Biol.
38
737-751
The mechanism by which DNA adenine methylase and PapI activate the pap epigenetic switch
2003
Hernday, A.D.; Braaten, B.A.; Low, D.A.
Mol. Cell
12
947-957
Structure of the bacteriophage T4 DNA adenine methyltransferase
2003
Yang, Z.; Horton, J.R.; Zhou, L.; Zhang, X.J.; Dong, A.; Zhang, X.; Schlagman, S.L.; Kossykh, V.; Hattman, S.; Cheng, X.
Nat. Struct. Biol.
10
849-855
Symmetry elements in DNA structure important for recognition/methylation by DNA [amino]-methyltransferases
2004
Zinoviev, V.V.; Yakishchik, S.I.; Evdokimov, A.A.; Malygin, E.G.; Hattman, S.
Nucleic Acids Res.
32
3930-3934
Structure, function and mechanism of exocyclic DNA methyltransferases
2006
Bheemanaik, S.; Reddy, Y.V.; Rao, D.N.
Biochem. J.
399
177-190
DNA-[adenine] methylation in lower eukaryotes
2005
Hattman, S.
Biochemistry (Moscow)
70
550-558
DNA adenine methyltransferase influences the virulence of Aeromonas hydrophila
2006
Erova, T.E.; Pillai, L.; Fadl, A.A.; Sha, J.; Wang, S.; Galindo, C.L.; Chopra, A.K.
Infect. Immun.
74
410-424
Mutations within the catalytic motif of DNA adenine methyltransferase (Dam) of Aeromonas hydrophila cause the virulence of the Dam-overproducing strain to revert to that of the wild-type phenotype
2006
Erova, T.E.; Fadl, A.A.; Sha, J.; Khajanchi, B.K.; Pillai, L.L.; Kozlova, E.V.; Chopra, A.K.
Infect. Immun.
74
5763-5772
Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase
2006
Horton, J.R.; Liebert, K.; Bekes, M.; Jeltsch, A.; Cheng, X.
J. Mol. Biol.
358
559-570
Structural model for the multisubunit Type IC restriction-modification DNA methyltransferase M.EcoR124I in complex with DNA
2006
Obarska, A.; Blundell, A.; Feder, M.; Vejsadova, S.; Sisakova, E.; Weiserova, M.; Bujnicki, J.M.; Firman, K.
Nucleic Acids Res.
34
1992-2005
Dimerization of the bacterial RsrI N6-adenine DNA methyltransferase
2006
Thomas, C.B.; Gumport, R.I.
Nucleic Acids Res.
34
806-815
MmeI: a minimal Type II restriction-modification system that only modifies one DNA strand for host protection
2008
Morgan, R.D.; Bhatia, T.K.; Lovasco, L.; Davis, T.B.
Nucleic Acids Res.
36
6558-6570
The Helicobacter pylori HpyAXII restriction-modification system limits exogenous DNA uptake by targeting GTAC sites but shows asymmetric conservation of the DNA methyltransferase and restriction endonuclease components
2008
Humbert, O.; Salama, N.R.
Nucleic Acids Res.
36
6893-6906
Role of histidine residues in EcoP15I DNA methyltransferase activity as probed by chemical modification and site-directed mutagenesis
2008
Jois, P.; Madhu, N.; Rao, D.
Biochem. J.
410
543-553
Escherichia coli DNA adenine methyltransferase: intrasite processivity and substrate-induced dimerization and activation
2009
Coffin, S.R.; Reich, N.O.
Biochemistry
48
7399-7410
Activation and inhibition of DNA methyltransferases by S-adenosyl-L-homocysteine analogues
2008
Kumar, R.; Srivastava, R.; Singh, R.; Surolia, A.; Rao, D.
Bioorg. Med. Chem.
16
2276-2285
Transition from EcoDam to T4Dam DNA recognition mechanism without loss of activity and specificity
2009
Elsawy, H.; Podobinschi, S.; Chahar, S.; Jeltsch, A.
ChemBioChem
10
2488-2493
Clocks and switches: bacterial gene regulation by DNA adenine methylation
2008
Low, D.; Casadesus, J.
Curr. Opin. Microbiol.
11
106-112
Characterization of the NgoAXP: phase-variable type III restriction-modification system in Neisseria gonorrhoeae
2009
Adamczyk-Poplawska, M.; Lower, M.; Piekarowicz, A.
FEMS Microbiol. Lett.
300
25-35
Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and more
2009
Marinus, M.G.; Casadesus, J.
FEMS Microbiol. Rev.
33
488-503
Regulation of Salmonella enterica pathogenicity island 1 (SPI-1) by DNA adenine methylation
2009
Lopez-Garrido, J.; Casadesus, J.
Genetics
184
637-649
Structural and dynamics study of DNA dodecamer duplexes that contain un-, hemi-, or fully methylated GATC sites
2008
Bang, J.; Bae, S.H.; Park, C.J.; Lee, J.H.; Choi, B.S.
J. Am. Chem. Soc.
130
17688-17696
Regulation of the Salmonella enterica std fimbrial operon by DNA adenine methylation, SeqA, and HdfR
2008
Jakomin, M.; Chessa, D.; Baeumler, A.J.; Casadesus, J.
J. Bacteriol.
190
7406-7413
Modulation of Escherichia coli DNA methyltransferase activity by biologically derived GATC-flanking sequences
2008
Coffin, S.R.; Reich, N.O.
J. Biol. Chem.
283
20106-20116
Escherichia coli DNA adenine methyltransferase: the structural basis of processive catalysis and indirect read-out
2009
Coffin, S.R.; Reich, N.O.
J. Biol. Chem.
284
18390-18400
DNA adenine methylation of sams1 gene in symbiont-bearing Amoeba proteus
2008
Jeon, T.J.
J. Microbiol.
46
564-570
Competitive Lrp and Dam assembly at the pap regulatory region: implications for mechanisms of epigenetic regulation
2008
Peterson, S.N.; Reich, N.O.
J. Mol. Biol.
383
92-105
Changing the DNA recognition specificity of the EcoDam DNA-(adenine-N6)-methyltransferase by directed evolution
2010
Chahar, S.; Elsawy, H.; Ragozin, S.; Jeltsch, A.
J. Mol. Biol.
395
79-88
M1.Mboll and M2.Mboll type IIS methyltransferases: different specificities, the same target
2009
Furmanek-Blaszk, B.; Boratynski, R.; Zolcinska, N.; Sektas, M.
Microbiology
155
1111-1121
-
Purification and properties of recombinant DNA methyltransferase M2.BstSE of the BstSEI nickase-modification system
2009
Chernukhin, V.; Seggewiss, J.; Kashirina, Y.; Gonchar, D.; Degtyarev, S.
Mol. Biol.
43
8-15
Insensitivity of chloroplast gene expression to DNA methylation
2009
Ahlert, D.; Stegemann, S.; Kahlau, S.; Ruf, S.; Bock, R.
Mol. Gen. Genet.
282
17-24
The MmeI family: type II restriction-modification enzymes that employ single-strand modification for host protection
2009
Morgan, R.D.; Dwinell, E.A.; Bhatia, T.K.; Lang, E.M.; Luyten, Y.A.
Nucleic Acids Res.
37
5208-5221
DNA adenine methylase is involved in the pathogenesis of Edwardsiella tarda
2010
Sun, K.; Jiao, X.D.; Zhang, M.; Sun, L.
Vet. Microbiol.
141
149-154
Identification of holocarboxylase synthetase chromatin binding sites in human mammary cell lines using the DNA adenine methyltransferase identification technology
2011
Singh, D.; Pannier, A.; Zempleni, J.
Anal. Biochem.
413
55-59
Using the fluorescence decay of 2-aminopurine to investigate conformational change in the recognition sequence of the EcoRV DNA-(adenine-N6)-methyltransferase on enzyme binding
2012
Bonnist, E.Y.; Liebert, K.; Dryden, D.T.; Jeltsch, A.; Jones, A.C.
Biophys. Chem.
160
28-34
Characterization of an N6 adenine methyltransferase from Helicobacter pylori strain 26695 which methylates adjacent adenines on the same strand
2010
Kumar, R.; Mukhopadhyay, A.K.; Rao, D.N.
FEBS J.
277
1666-1683
DNA adenine methyltransferase (Dam) controls the expression of the cytotoxic enterotoxin (act) gene of Aeromonas hydrophila via tRNA modifying enzyme-glucose-inhibited division protein (GidA)
2012
Erova, T.E.; Kosykh, V.G.; Sha, J.; Chopra, A.K.
Gene
498
280-287
Proximal recognition sites facilitate intrasite hopping by DNA adenine methyltransferase: Mechanistic exploration of epigenetic gene regulation
2012
Pollak, A.J.; Reich, N.O.
J. Biol. Chem.
287
22873-22881
The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner
2012
Albu, R.F.; Jurkowski, T.P.; Jeltsch, A.
Nucleic Acids Res.
40
1708-1716
Novel non-specific DNA adenine methyltransferases
2012
Drozdz, M.; Piekarowicz, A.; Bujnicki, J.M.; Radlinska, M.
Nucleic Acids Res.
40
2119-2130
Characterization of DNA methyltransferase specificities using single-molecule, real-time DNA sequencing
2012
Clark, T.A.; Murray, I.A.; Morgan, R.D.; Kislyuk, A.O.; Spittle, K.E.; Boitano, M.; Fomenkov, A.; Roberts, R.J.; Korlach, J.
Nucleic Acids Res.
40
e29
Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695
2011
Banerjee, A.; Rao, D.N.
PLoS ONE
6
e16810
DNA adenine methyltransferase facilitated diffusion is enhanced by protein-DNA roadblock complexes that induce DNA looping
2015
Pollak, A.; Reich, N.
Biochemistry
54
2181-2192
Increasing DNA substrate specificity of the EcoDam DNA-(adenine N6)-methyltransferase by site-directed mutagenesis
2014
Elsawy, H.; Chahar, S.
Biochemistry
79
1262-1266
Investigation of the C-terminal domain of the bacterial DNA-(adenine N6)-methyltransferase CcrM
2015
Maier, J.; Albu, R.; Jurkowski, T.; Jeltsch, A.
Biochimie
119
60-67
Dynamics and reactivity in Thermus aquaticus N6-adenine methyltransferase
2014
Aranda, J.; Zinovjev, K.; Roca, M.; Tunon, I.
J. Am. Chem. Soc.
136
16227-16239
Bacteriophage adenine methyltransferase: A life cycle regulator? Modelled using Vibrio harveyi myovirus like
2012
Bochow, S.; Elliman, J.; Owens, L.
J. Appl. Microbiol.
113
1001-1013
Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: Potential implications for methylation-independent transcriptional repression
2015
Horton, J.; Zhang, X.; Blumenthal, R.; Cheng, X.
Nucleic Acids Res.
43
4296-4308
Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes
2014
Kubicek-Sutherland, J.; Heithoff, D.; Ersoy, S.; Shimp, W.; Mahan, M.
Vaccine
32
1451-1459
Direct and continuous fluorescence-based measurements of Pyrococcus horikoshii DNA N-6 adenine methyltransferase activity
2011
Maynard-Smith, M.; McKelvie, J.; Wood, R.; Harmer, J.; Ranasinghe, R.; Williams, C.; Coomber, D.; Stares, A.; Roach, P.
Anal. Biochem.
418
204-212
Identification of a DNA N6-adenine methyltransferase complex and its impact on chromatin organization
2019
Beh, L.Y.; Debelouchina, G.T.; Clay, D.M.; Thompson, R.E.; Lindblad, K.A.; Hutton, E.R.; Bracht, J.R.; Sebra, R.P.; Muir, T.W.; Landweber, L.F.
Cell
177
1781-1796
Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro
2019
Woodcock, C.; Yu, D.; Hajian, T.; Li, J.; Huang, Y.; Dai, N.; Correa, I.J.; Wu, T.; Vedadi, M.; Zhang, X.; Cheng, X.
Cell Discov.
5
63
DNA adenine methyltransferase (Dam) overexpression impairs Photorhabdus luminescens motility and virulence
2017
Payelleville, A.; Lanois, A.; Gislard, M.; Dubois, E.; Roche, D.; Cruveiller, S.; Givaudan, A.; Brillard, J.
Front. Microbiol.
8
1671
The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site
2019
Horton, J.R.; Woodcock, C.B.; Opot, S.B.; Reich, N.O.; Zhang, X.; Cheng, X.
Nat. Commun.
10
4600
A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription
2019
Wang, Y.; Sheng, Y.; Liu, Y.; Zhang, W.; Cheng, T.; Duan, L.; Pan, B.; Qiao, Y.; Liu, Y.; Gao, S.
Nucleic Acids Res.
47
11771-11789
Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori
2016
Ma, B.; Ma, J.; Liu, D.; Guo, L.; Chen, H.; Ding, J.; Liu, W.; Zhang, H.
Oncotarget
7
40965-40977
Isospecific adenine DNA methyltransferases show distinct preferences towards DNA substrates
2018
Wons, E.; Mruk, I.; Kaczorowski, T.
Sci. Rep.
8
8243
close all tables 
open all tables
top
