Ligand oxypurinol

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Basic Ligand Information

Molecular Structure
Picture of oxypurinol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H4N4O2
oxypurinol
HXNFUBHNUDHIGC-UHFFFAOYSA-N
Synonyms:
4,6-dihydroxypyrazolo(3,4-d)pyrimidine, 4,6-dihydroxypyrazolo[3,4-d]-pyrimidine, 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine, alloxanthine, Oxipurinol, Oxoallopurinol

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-hydroxypyrazolo(3,4-d)pyrimidine + O2 + H2O = 4,6-dihydroxypyrazolo(3,4-d)pyrimidine + H2O2
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-phospho-alpha-D-ribose 1-diphosphate + 4,6-dihydroxypyrazolo[3,4-d]pyrimidine = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
allopurinol + H2O + O2 = oxypurinol + H2O2
show the reaction diagram
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4-hydroxypyrazolo(3,4-d)pyrimidine + O2 + H2O = 4,6-dihydroxypyrazolo(3,4-d)pyrimidine + H2O2
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (3 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.001
-
-
0.81
-
-
0.31
-
-

References & Links

Links to other databases for oxypurinol

ChEBI
PubChem
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PubChem