Ligand L-sorbose

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Basic Ligand Information

Molecular Structure
Picture of L-sorbose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12O6
L-sorbose
BJHIKXHVCXFQLS-OTWZMJIISA-N
Synonyms:
2-dehydro-L-sorbose, L-sorbose[side 1], L-xylo-hex-2-ulose
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for L-sorbose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-sorbose + O2 = 5-dehydro-D-fructose + H2O2
show the reaction diagram
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L-sorbose + O2 = 5-dehydro-D-fructose + H2O2
show the reaction diagram
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L-sorbose + ferricenium ion = ? + ferrocene
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[protein]-Npi-phospho-L-histidine + L-sorbose[side 1] = [protein]-L-histidine + L-sorbose 1-phosphate[side 2]
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-iditol + NAD+ = L-sorbose + NADH
show the reaction diagram
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D-sorbitol + acceptor = L-sorbose + reduced acceptor
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (51 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-sorbose + NADPH + H+ = L-sorbitol + NADP+
show the reaction diagram
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L-sorbose + NADPH = ? + NADP+
show the reaction diagram
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L-sorbose + NADPH = L-sorbitol + NADP+
show the reaction diagram
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L-sorbose + NADH + H+ = ?
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L-sorbose + 2,6-dichlorophenolindophenol = ? + reduced 2,6-dichlorophenolindophenol
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D-Glucose + L-sorbose = ?
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UDP-alpha-D-glucose + L-sorbose = ?
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sucrose + L-sorbose = ?
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soluble starch + L-sorbose = ?
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L-sorbose + 1,5-anhydro-D-glucitol = ? + phosphate
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starch + L-sorbose = ?
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L-sorbose + beta-D-glucose 1-phosphate = 1,4-alpha-D-glucopyranosyl-[1,2-beta-D-glucopyranosyl]-D-glucose + phosphate
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[protein]-Npi-phospho-L-histidine + L-sorbose[side 1] = [protein]-L-histidine + L-sorbose 1-phosphate[side 2]
show the reaction diagram
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ATP + L-sorbose = ?
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phosphatidylcholine + L-sorbose = phosphatidylsorbose + choline
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2-nitrophenyl beta-D-galactopyranoside + L-sorbose = beta-D-galactopyranosyl-(1-1)-L-sorbose + 2-nitrophenol
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L-sorbose = L-gulose + L-idose
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L-sorbose = L-gulose
show the reaction diagram
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L-Sorbose + alpha-D-glucose 1-phosphate = L-Sorbose 6-phosphate + D-glucose
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (29 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-sorbitol + NAD+ = L-sorbose + NADH + H+
show the reaction diagram
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L-iditol + NAD+ = L-sorbose + NADH
show the reaction diagram
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5-keto-D-fructose + NADPH = L-sorbose + NADP+
show the reaction diagram
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L-iditol + NAD+ = L-sorbose + NADH
show the reaction diagram
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5-keto-D-fructose + NADPH = L-sorbose + NADP+
show the reaction diagram
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5-dehydro-D-fructose + NADPH + H+ = L-sorbose + NADP+
show the reaction diagram
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D-sorbitol + NAD+ = L-sorbose + NADH + H+
show the reaction diagram
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L-sorbitol + NAD+ = L-sorbose + NADH + H+
show the reaction diagram
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D-sorbitol + NAD+ = L-sorbose + NADH + H+
show the reaction diagram
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D-sorbitol + NADP+ = L-sorbose + NADPH + H+
show the reaction diagram
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L-sorbose + O2 = 2-dehydro-L-sorbose + H2O2
show the reaction diagram
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D-sorbitol + acceptor = L-sorbose + reduced acceptor
show the reaction diagram
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L-sorbose + 1,4-benzoquinone = 2-dehydro-L-sorbose + hydroquinone
show the reaction diagram
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L-glyceraldehyde = L-sorbose
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L-gulose = L-sorbose
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L-gulose = L-sorbose
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibits the oxidation of gluconolactone
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0.4 M, 45% inhibition
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competitive
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (14 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
782
-
pH 7.5, 25°C, Michaelis-Menten kinetics
216
-
35°C, pH 7.5, native enzyme
15.7
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with ferrocenium ion as cosubstrate, pH and temperature not specified in the publication
11.2
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at pH 8.5 and 40°C
0.568
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pH 8.0, 37°C
0.38
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in 50 mM glycine-NaOH buffer (pH 9.0), at 40°C

KM Value (41 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
22
-
-
0.9
-
35°C, pH 7.5, native enzyme
217.4
-
-
130
-
-
28.1
-
pH 8.0, 37°C
40
-
in 50 mM glycine-NaOH buffer (pH 9.0), at 40°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2
-
pH 7.5, 25°C

References & Links

Links to other databases for L-sorbose

ChEBI
PubChem
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PubChem