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Thermostable valyl-tRNA, isoleucyl-tRNA and methionyl-tRNA synthetases from an extreme thermophile Thermus thermophilus HB8. Protein structure and Zn2+ binding
1984
Kohda, D.; Yokoyama, S; Miyazawa, T.
FEBS Lett.
174
20-23
Relationship of protein structure of isoleucyl-tRNA synthetase with pseudomonic acid resistance of Escherichia coli
1994
Yanagisawa, T.; Lee, J.T.; Wu, H.C.; Kawakami, M.
J. Biol. Chem.
269
24304-24309
C-terminal zinc-containing peptide required for RNA recognition by a class I tRNA synthetase
1996
Glasfeld, E.; Landro, J.A.; Schimmel, P.
Biochemistry
35
4139-4145
Proofreading in trans by an aminoacyl-tRNA synthetase. A model for single site editing by isoleucyl-tRNA synthetase
1996
Jakubowski, H.
Nucleic Acids Res.
24
2505-2510
Mutation of the carboxy terminal zinc finger of E. coli isoleucyl-tRNA synthetase alters zinc binding and aminoacylation activity
1995
Zhou, L.; Rosevear, P.R.
Biochem. Biophys. Res. Commun.
216
648-654
Switching recognition of two tRNA synthetases with an amino acid swap in a designed peptide
1995
Auld, D.S.; Schimmel., P.
Science
267
1994-1996
Thiol ligation of two zinc atoms to a class I tRNA synthetase. Evidence for unshared thiols and role in amino acid binding and utilization
1994
Landro, J.A.; Schmidt, E.; Schimmel, P.
Biochemistry
33
14213-14220
Probing the metal binding sites of E. coli isoleucyl-tRNA synthetase
1994
Xu, B.; Trawick, B.; Krudy, G.A.; Phillips, R.M.; Zhou.L.; Rosevear, P.R.
Biochemistry
33
398-402
Analysis of the isoleucyl-tRNA synthetase reaction by total rate equation. Magnesium and spermidine in the tRNA kinetics
1992
Airas, R.K.
Eur. J. Biochem.
210
451-454
Evidence for distinct locations for metal binding sites in two closely related class I tRNA synthetases
1993
Schimmel, P.; Landro, J.A.; Schidt, E.
J. Biomol. Struct. Dyn.
11
571-581
Zinc-dependent tRNA binding by a peptide element within a tRNA synthetase
1997
Glasfeld, E.; Schimmel, P.
Biochemistry
36
6739-6744
Expression and characterization of a recombinant yeast isoleucyl-tRNA synthetase
1991
Racher, K.I.; Kalmar, G.B.; Borgford, T.J.
J. Biol. Chem.
266
17158-17164
Structure of the yeast isoleucyl-tRNA synthetase gene (ILS1). DNA-sequence, amino-acid sequence of the proteolytic peptides of the enzyme and comparison of the structure to those of other known aminoacyl-tRNA synthetases
1987
Englisch, U.; Englisch, S.; Markmeyer, P.; Schischkoff, J.; Sterbach, H.; Kratzin, H.; Cramer, F.
Biol. Chem. Hoppe-Seyler
368
971-979
Isoleucyl-tRNA synthetase of Methanobacterium thermoautotrophicum Marburg. Cloning of the gene, nucleotide sequence, and localization of a base change conferring resistance to pseudomonic acid
1991
Jenal.U.; Rechsteiner, T.; Tan, P.Y.; Buhlmann, E.; Meile, L.; Leisinger, T.
J. Biol. Chem.
266
10570-10577
Isoleucyl-transfer ribonucleic acid synthetase from Bacillus stearothermophilus. Properties of the enzyme
1972
Charlier, J.; Grosjean, H.
Eur. J. Biochem.
25
163-174
Comparative studies on the isoleucyl-tRNA synthetases from Bacillus stearothermophilus and Escherichia coli. II. The effect of magnesium ions in the transacylation reaction
1971
Grosjean, H.; Charlier, J.
FEBS Lett.
18
342-346
Cation requirements of isoleucyl-tRNA synthetase from Escherichia coli
1972
Steinmetz Kayne , M.; Cohn, M.
Biochem. Biophys. Res. Commun.
46
1285-1291
Isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B. Effects of magnesium and spermine on the amino acid activation reaction
1973
Holler, E.
Biochemistry
12
1142-1149
Isolation and properties of isoleucyl-tRNA synthetase from Escherichia coli MRE 600
1973
Durekovic, A.; Flossdorf, J.; Kula, M.R.
Eur. J. Biochem.
36
528-533
The effect of spermine anf Mg2+ on the catalytic mechanism of isoleucine:tRNA ligase
1975
Carr, A.C.; Igloi, G.L.; Penzer, G.R.; Plumbridge, J.A.
Eur. J. Biochem.
54
169-173
-
Studies on isoleucyl-tRNA synthetase of an extreme thermophile, Thermus thermophilus HB8
1975
Wakagi, T.; Ohta, T.; Imahori, K.
Agric. Biol. Chem.
39
1573-1580
-
L-Isoleucyl-tRNA synthetase aus E. coli. pH-Abhängigkeit der Enzym-Substrat Komplexbildung
1976
Hammer-Raber, B.; Rainey, P.M.; Holler, E.
Hoppe-Seyler's Z. Physiol. Chem.
357
295
Purification of isoleucyl transfer ribonucleic acid synthetase by affinity chromatography on blue dextran-Sepharose
1976
Moe, J.G.; Piszkiewicz, D.
FEBS Lett.
72(1)
147-150
Valyl-tRNA, isoleucyl-tRNA and tyrosyl-tRNA synthetase from baker's yeast. Substrate specificity with regard to ATP analogs and mechanism of the aminoacylation reaction
1976
Freist, W.; von der Haar, F.; Faulhammer, H.; Cramer, F.
Eur. J. Biochem.
66
493-497
Effect of polyamines on isoleucyl-tRNA formation by rat liver isoleucyl-tRNA synthetase
1978
Igarashi, K.; Eguchi, K.; Tanaka, M.; Hirose, S.
Eur. J. Biochem.
82
301-307
Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Escherichia coli by pseudomonic acid
1978
Hughes, J.; Mellows, G.
Biochem. J.
176
305-318
Isoleucyl-tRNA synthetase from baker's yeast
1981
Freist, W.; von der Haar, F.; Cramer, F.
Eur. J. Biochem.
119
151-164
Purification and characterization of the isoleucyl-tRNA synthetase component from the high molecular weight complex of sheep liver. A hydrophobic metalloprotein
1985
Lazard, M.; Mirande, M.; Waller, J.P.
Biochemistry
24
5099-5106
-
Mutation to pseudomonic acid resistance of Methanobacterium thermoautotrophicum leads to an altered isoleucyl-tRNA synthetase
1986
Kiener, A.; Rechsteiner, T.; Leisinger, T.
FEMS Microbiol. Lett.
33
15-18
Isoleucyl-tRNA synthetase from baker's yeast and from Escherichia coli MRE 600. Discrimination of 20 amino acids in aminoacylation of tRNAIle-C-C-A(3'NH2)
1987
Freist, W.; Sternbach, H.; Cramer, F.
Eur. J. Biochem.
169
33-39
CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function
2000
Chen, J.F.; Guo, N.N.; Li, T.; Wang, E.D.; Wang, Y.L.
Biochemistry
39
6726-6731
Misacylation and editing by Escherichia coli valyl-tRNA synthetase: evidence for two tRNA binding sites
2001
Tardif, K.D.; Liu, M.; Vitseva, O.; Hou, Y.M.; Horowitz, J.
Biochemistry
40
8118-8125
Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207
2003
Crasto, C.F.; Forrest, A.K.; Karoli, T.; March, D.R.; Mensah, L.; O'Hanlon, P.J.; Nairn, M.R.; Oldham, M.D.; Yue, W.; Banwell, M.G.; Easton, C.J.
Bioorg. Med. Chem.
11
2687-2694
Ester and hydroxamate analogues of methionyl and isoleucyl adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases
2001
Lee, J.; Kang, S.U.; Kim, S.Y.; Kim, S.E.; Kang, M.K.; Jo, Y.J.; Kim, S.
Bioorg. Med. Chem. Lett.
11
961-964
Vanilloid and isovanilloid analogues as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases
2001
Lee, J.; Kang, S.U.; Kim, S.Y.; Kim, S.E.; Job, Y.J.; Kim, S.
Bioorg. Med. Chem. Lett.
11
965-968
N-Alkoxysulfamide, N-hydroxysulfamide, and sulfamate analogues of methionyl and isoleucyl adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases
2003
Lee, J.; Kim, S.E.; Lee, J.Y.; Kim, S.Y.; Kang, S.U.; Seo, S.H.; Chun, M.W.; Kang, T.; Choi, S.Y.; Kim, H.O.
Bioorg. Med. Chem. Lett.
13
1087-1092
Characterization of isoleucyl-tRNA synthetase from Staphylococcus aureus. I: Kinetic mechanism of the substrate activation reaction studied by transient and steady-state techniques
1998
Pope, A.J.; Lapointe, J.; Mensah, L.; Benson, N.; Brown, M.J.; Moore, K.J.
J. Biol. Chem.
273
31680-31690
Characterization of isoleucyl-tRNA synthetase from Staphylococcus aureus. II. Mechanism of inhibition by reaction intermediate and pseudomonic acid analogues studied using transient and steady-state kinetics
1998
Pope, A.J.; Moore, K.J.; McVey, M.; Mensah, L.; Benson, N.; Osbourne, N.; Broom, N.; Brown, M.J.; O'Hanlon, P.
J. Biol. Chem.
273
31691-31701
Effects of substrate and inhibitor binding on proteolysis of isoleucyl-tRNA synthetase from Staphylococcus aureus
1998
Pope, A.J.; McVey, M.; Fantom, K.; Moore, K.J.
J. Biol. Chem.
273
31702-31706
Active aminoacyl-tRNA synthetases are present in nuclei as a high molecular weight multienzyme complex
2000
Nathanson, L.; Deutscher, M.P.
J. Biol. Chem.
275
31559-31562
Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase
2001
Nakama, T.; Nureki, O.; Yokoyama, S.
J. Biol. Chem.
276
47387-47393
How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense
2003
Yanagisawa, T.; Kawakami, M.
J. Biol. Chem.
278
25887-25894
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine
2004
Fukunaga, R.; Fukai, S.; Ishitani, R.; Nureki, O.; Yokoyama, S.
J. Biol. Chem.
279
8396-8402
Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase
2003
Lincecum, T.L., Jr.; Tukalo, M.; Yaremchuk, A.; Mursinna, R.S.; Williams, A.M.; Sproat, B.S.; Van Den Eynde, W.; Link, A.; Van Calenbergh, S.; Grotli, M.; Martinis, S.A.; Cusack, S.
Mol. Cell
11
951-963
Insights into editing from an Ile-tRNA synthetase structure with tRNAIle and mupirocin
1999
Silvian, L.F.; Wang, J.; Steitz, T.A.
Science
285
1074-1077
Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing
2009
Zhou, X.L.; Wang, E.D.
Biochem. Biophys. Res. Commun.
386
510-515
A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase
2009
Pang, Y.L.; Martinis, S.A.
Biochemistry
48
8958-8964
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