Ligand N3-methylcytosine
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Basic Ligand Information
Molecular Structure

C5H7N3O
N3-methylcytosine
KOLPWZCZXAMXKS-UHFFFAOYSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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N3-methylcytosine + 2-oxoglutarate + O2 = cytosine + formaldehyde + succinate + CO2
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Substrate in Enzyme-catalyzed Reactions (1 result)
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N3-methylcytosine + 2-oxoglutarate + O2 = cytosine + formaldehyde + succinate + CO2
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Product in Enzyme-catalyzed Reactions (1 result)
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alkylated DNA + H2O = 3-methyladenine + N3-methylcytosine + 1,N6-ethenoadenine + DNA
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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ABH2 couples regulation of ribosomal DNA transcription with DNA alkylation repair
2013
Li, P.; Gao, S.; Wang, L.; Yu, F.; Li, J.; Wang, C.; Li, J.; Wong, J.
Cell Rep.
4
817-829
Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response
2013
Vagbo, C.B.; Svaasand, E.K.; Aas, P.A.; Krokan, H.E.
DNA Repair
12
188-195
Links to other databases for N3-methylcytosine