Ligand (3R)-3-methyl-D-ornithine
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
Molecular Structure

C6H14N2O2
(3R)-3-methyl-D-ornithine
HYUPFEBCCJWDJX-RFZPGFLSSA-N
(2R,3R)-3-methylornithine
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + (3R)-3-methyl-D-ornithine + L-lysine = ADP + phosphate + N6-[(3R)-3-methyl-D-ornithinyl]-L-lysine
-
Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + (3R)-3-methyl-D-ornithine + L-lysine = ADP + phosphate + N6-[(3R)-3-methyl-D-ornithinyl]-L-lysine
-
Product in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
L-lysine = (3R)-3-methyl-D-ornithine
-
-
3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Enzyme Kinetic Parameters
References & Links
Literature References (4)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Functional context, biosynthesis, and genetic encoding of pyrrolysine
2011
Gaston, M.; Jiang, R.; Krzycki, J.
Curr. Opin. Microbiol.
14
342-349
Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine structure and reaction mechanism of PylC at 1.5 A resolution
2012
Quitterer, F.; List, A.; Beck, P.; Bacher, A.; Groll, M.
J. Mol. Biol.
424
270-282
D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine
2011
Cellitti, S.; Ou, W.; Chiu, H.; Gruenewald, J.; Jones, D.; Hao, X.; Fan, Q.; Quinn, L.; Ng, K.; Anfora, A.; Lesley, S.; Uno, T.; Brock, A.; Geierstanger, B.
Nat. Chem. Biol.
7
528-530
The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine
2011
Gaston, M.; Zhang, L.; Green-Church, K.; Krzycki, J.
Nature
471
647-650
Links to other databases for (3R)-3-methyl-D-ornithine