Ligand 1-(5-phosphoribosyl)-AMP

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Basic Ligand Information

Molecular Structure
Picture of 1-(5-phosphoribosyl)-AMP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H23N5O14P2
1-(5-phosphoribosyl)-AMP
RTQMRTSPTLIIHM-KEOHHSTQSA-N
Synonyms:
1-(5-phospho-beta-D-ribosyl)-AMP, N1-(5-phospho-D-ribosyl)-AMP, N1-(5-phosphoribosyl)-AMP, phosphoribosyl-AMP, phosphoribosyl adenosine monophosphate


Show all pahtways known for Show all BRENDA pathways known for 1-(5-phosphoribosyl)-AMP

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cyclic ADP-ribose + H2O = N1-(5-phosphoribosyl)-AMP + phosphate
show the reaction diagram
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1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
46% inhibition at 25 nM, 87% inhibition at 50 nM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0000162
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References & Links

Links to other databases for 1-(5-phosphoribosyl)-AMP

ChEBI
PubChem
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PubChem