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Ligand ubiquinol-10 Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C5 9 H9 2 O4
ubiquinol-10
QNTNKSLOFHEFPK-AMJCLVIFSA-N
reduced ubiquinone Q10, ubiquinol 10
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2 ubiquinol-10 + O2 = 2 ubiquinone-10 + 2 H2O
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In Vivo Product in Enzyme-catalyzed Reactions (6 results)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ubiquinone-10 + NAD(P)H = ubiquinol-10 + NAD(P)+
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NADPH + H+ + ubiquinone-10 = NADP+ + ubiquinol-10
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S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10 + H+
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NADH + H+ + ubiquinone-10 = NAD+ + ubiquinol-10
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ubiquinone-10 + ferricytochrome c = ubiquinol-10 + ferrocytochrome c + 2 H+
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NADH + ubiquinone-10 = NAD+ + ubiquinol-10
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Substrate in Enzyme-catalyzed Reactions (3 results)
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2 ubiquinol-10 + O2 = 2 ubiquinone-10 + 2 H2O
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ubiquinol-10 + O2 + H+[side 1] = ubiquinone-10 + H2O + H+[side 2]
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ubiquinol 10 + cytochrome c = ubiquinone 10 + reduced cytochrome c
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Product in Enzyme-catalyzed Reactions (20 results)
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D-2-hydroxybutyrate + ubiquinone-10 = 2-oxobutyrate + ubiquinol-10
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D-glycerate + ubiquinone-10 = ? + ubiquinol-10
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D-lactate + ubiquinone-10 = pyruvate + ubiquinol-10
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L-lactate + ubiquinone-10 = pyruvate + ubiquinol-10
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D-2-hydroxybutyrate + ubiquinone-10 = ? + ubiquinol-10
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D-glycerate + ubiquinone-10 = ? + ubiquinol-10
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D-lactate + ubiquinone-10 = pyruvate + ubiquinol-10
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L-lactate + ubiquinone-10 = pyruvate + ubiquinol-10
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NADH + H+ + ubiquinone-10 = NAD+ + ubiquinol-10
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NADPH + H+ + ubiquinone-10 = NADP+ + ubiquinol-10
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NADH + H+ + ubiquinone-10 = NAD+ + ubiquinol-10
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ubiquinone-10 + NAD(P)H = ubiquinol-10 + NAD(P)+
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NADH + ubiquinone-10 = NAD+ + ubiquinol-10
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NADPH + H+ + ubiquinone-10 = NADP+ + ubiquinol-10
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S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10 + H+
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NADH + H+ + ubiquinone-10 = NAD+ + ubiquinol-10
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NADH + ubiquinone-10 + 5 H+[side 1] = NAD+ + ubiquinol-10 + 4 H+[side 2]
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NADH + ubiquinone-10 = NAD+ + ubiquinol-10
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ubiquinone-10 + ferricytochrome c = ubiquinol-10 + ferrocytochrome c + 2 H+
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NADH + ubiquinone-10 = NAD+ + ubiquinol-10
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Enzyme Kinetic Parameters
KM Value (5 results)
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0.96
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pH 7.4, temperature not specified in the publication
References & Links Literature References (6)
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Characterization of purified cytochrome b-c1 complex from Rhodopseudomonas sphaeroides R-26
1984
Yu, L.; Mei, Q.C.; Yu, C.A.
J. Biol. Chem.
259
5752-5760
The small molecular mass ubiquinone-binding protein (QPc-9.5 kDa) in mitochondrial ubiquinol-cytochrome c reductase: isolation, ubiquinone-binding domain, and immunoinhibition
1990
Usui, S.; Yu, L.; Yu, C.A.
Biochemistry
29
4618-4626
Oxidation process of bovine heart ubiquinol-cytochrome c reductase as studied by stopped-flow rapid-scan spectrophotometry and simulations based on the mechanistic Q cycle model
1997
Orii, Y.; Miki, T.
J. Biol. Chem.
272
17594-17604
Cyanide-insensitive quinol oxidase (CIO) from Gluconobacter oxydans is a unique terminal oxidase subfamily of cytochrome bd
2013
Miura, H.; Mogi, T.; Ano, Y.; Migita, C.T.; Matsutani, M.; Yakushi, T.; Kita, K.; Matsushita, K.
J. Biochem.
153
535-545
Characterization of a quinole-oxidase activity in crude extracts of Thermoplasma acidophilum and isolation of an 18-kDa cytochrome
1991
Gartner, P.
Eur. J. Biochem.
200
215-222
Biochemical characterization and inhibition of the alternative oxidase enzyme from the fungal phytopathogen Moniliophthora perniciosa
2020
Barsottini, M.; Copsey, A.; Young, L.; Baroni, R.; Cordeiro, A.; Pereira, G.; Moore, A.
Commun. Biol.
3
263
Links to other databases for ubiquinol-10
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