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BRENDA support

Ligand UpA

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Basic Ligand Information

Molecular Structure
Picture of UpA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H24N7O12P
UpA
SWTWQWKNQDDGCS-KPKSGTNCSA-N
Synonyms:
uridylyl-3',5'-adenosine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UpA + H2O = 5'-AMP + uridine
show the reaction diagram
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uridylyl-3',5'-adenosine + H2O = ?
show the reaction diagram
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UpA + H2O = ?
show the reaction diagram
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UpA + H2O = adenosine + 3'-UMP
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pro-uPa + H2O = uPa
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
uPA regulates SHP-2 phosphorylation, stimulates its catalytic activity and association with PDGFR-beta and with lipid rafts
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Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.79
-
-

References & Links

Links to other databases for UpA

ChEBI
PubChem
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PubChem