Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Involvement of 4-hydroxymandelic acid in the degradation of mandelic acid by Pseudomonas convexa
1976
Bhat, S.G.; Vaidyanathan, C.S.
J. Bacteriol.
127
1108-1118
-
Aromatic amino acid hydroxylases
1987
Kaufman, S.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
18
217-282
3,4-Dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases
1984
Koizumi, S.; Matsushima, Y.; Nagatsu, T.; Linuma, H.; Takeuchi, T.; Umezawa, H.
Biochim. Biophys. Acta
789
111-118
Tryptophan 5-monooxygenase from rat brain stem
1987
Fujisawa, H.; Nakata, H.
Methods Enzymol.
142
83-87
Tryptophan 5-monooxygenase from mouse mastocytoma: high-performance liquid chromatography assay
1987
Hasegawa, H.; Ichiyama, A.
Methods Enzymol.
142
88-92
Tryptophan 5-monooxygenase from mouse mastocytoma clone P815
1987
Fujisawa, H.; Nakata, H.
Methods Enzymol.
142
93-96
Simple and rapid purification of tryptophan 5-monooxygenase from rabbit brain by affinity chromatography
1981
Nakata, H.; Fujisawa, H.
J. Biochem.
90
567-569
Purification and some properties of bovine pineal tryptophan 5-monooxygenase
1974
Nukiwa, T.; Tohyama, C.; Okita, C.; Kataoka, T.; Ichiyama, A.
Biochem. Biophys. Res. Commun.
60
1029-1035
Tryptophan 5-monooxygenase from mouse mastocytoma P815. A simple purification and general properties
1982
Nakata, H.; Fujisawa, H.
Eur. J. Biochem.
124
595-601
Purification and properties of tryptophan 5-monooxygenase from rat brain-stem
1982
Nakata, H.; Fujisawa, H.
Eur. J. Biochem.
122
41-47
Tryptophan 5-hydroxylase. Rapid purification from whole rat brain and production of a specific antiserum
1985
Cash, C.D.; Vayer, P.; Mandel, P.; Maitre, M.
Eur. J. Biochem.
149
239-245
Properties of tryptophan hydroxylase from human carcinoid tumor
1977
Hosoda, S.; Nakamura, W.; Takatsuki, K.
Biochim. Biophys. Acta
482
27-34
Partial purification and characterization of tryptophan hydroxylase from rabbit hindbrain
1972
Friedman, P.A.; Kappelman, A.H.; Kaufman, S.
J. Biol. Chem.
247
4165-4173
Enzymic studies on the biosynthesis of serotonin in mammalian brain
1970
Ichiyama, A.; Nakamura, S.; Nishizuka, Y.; Hayaishi, O.
J. Biol. Chem.
245
1699-1709
Brain tryptophan hydroxylase: purification of, production of antibodies to, and cellular and ultrastructural localization in serotonergic neurons of rat midbrain
1975
Joh, T.H.; Shikimi, T.; Pickel, V.M.; Reis, D.J.
Proc. Natl. Acad. Sci. USA
72
3575-3579
Tryptophan hydroxylase. Purification and some properties of the enzyme from rabbit hindbrain
1975
Tong, J.H.; Kaufman, S.
J. Biol. Chem.
250
4152-4158
Characterization of yellowfin tuna (Thunnus albacares, Scombroidei) tryptophan hydroxylase
1997
Nagai, T.; Hamada, M.; Kai, N.; Tanoue, Y.; Nagayama, F.
Comp. Biochem. Physiol. B
116
161-165
Expression and characterization of the catalytic core of tryptophan hydroxylase
1998
Moran, G.R.; Daubner, S.C.; Fitzpatrick, P.F.
J. Biol. Chem.
273
12259-12266
Characterization of a stable form of tryptophan hydroxylase from the human parasite Schistosoma mansoni
1999
Hamdan, F.F.; Ribeiro, P.
J. Biol. Chem.
274
21746-21754
A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis
2001
Martinez, A.; Knappskog, P.M.; Haavik, J.
Curr. Med. Chem.
8
1077-1091
Phenylalanine as substrate and inhibitor of tyrosine hydroxylase
1967
Ikeda, M.; Levitt, M.; Udenfriend, S.
Arch. Biochem. Biophys.
120
420-427
A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines
1996
Hillas, P.J.; Fitzpatrick, P.F.
Biochemistry
35
6969-6975
Interaction of substrate and pterin cofactor with the metal of human tyrosine hydroxylase as determined by 1H-NMR
1993
Martinez, A.; Abeygunawardana, C.; Haavik, J.; Flatmark, T.; Mildvan, A.S.
Adv. Exp. Med. Biol.
338
77-80
Reversing the substrate specificities of phenylalanine and tyrosine hydroxylase: aspartate 425 of tyrosine hydroxylase is essential for L-DOPA formation
2000
Daubner, S.C.; Melendez, J.; Fitzpatrick, P.F.
Biochemistry
39
9652-9661
Mutation to phenylalanine of tyrosine 371 in tyrosine hydroxylase increases the affinity for phenylalanine
1998
Daubner, S.C.; Fitzpatrick, P.F.
Biochemistry
37
16440-16444
Purification and properties of benzoate-4-hydroxylase from a soil pseudomonad
1976
Reddy, C.C.; Vaidyanathan, C.S.
Arch. Biochem. Biophys.
177
488-498
Purification, properties and induction of a specific benzoate-4-hydroxylase from Aspergillus niger (UBC 814)
1975
Reddy, C.C.; Vaidyanathan, C.S.
Biochim. Biophys. Acta
384
46-57
Mandelic acid-4-hydroxylase, a new inducible enzyme from Pseudomonas convexa
1973
Bhat, S.G.; Ramanarayanan, M.; Vaidyanathan, C.S.
Biochem. Biophys. Res. Commun.
52
834-842
Purifications and properties of L-mandelate-4-hydroxylase from Pseudomonas convexa
1976
Bhat, S.G.; Vaidyanathan, C.S.
Arch. Biochem. Biophys.
176
314-323
Physarum polycephalum expresses a dihydropteridine reductase with selectivity for pterin substrates with a 6-(1', 2'-dihydroxypropyl) substitution
2003
Wild, C.; Golderer, G.; Grobner, P.; Werner-Felmayer, G.; Werner, E.R.
Biol. Chem.
384
1057-1062
Aroclor 1254 inhibits tryptophan hydroxylase activity in rat brain
2004
Khan, I.A.; Thomas, P.
Arch. Toxicol.
78
316-320
Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neutrotransmitters serotonin and melatonin
2002
Wang, L.; Erlandsen, H.; Haavik, J.; Knappskog, P.M.; Stevens, R.C.
Biochemistry
41
12569-12574
A second tryptophan hydroxylase isoform, TPH-2 mRNA, is increased by ovarian steroids in the raphe region of macaques
2005
Sanchez, R.L.; Reddy, A.P.; Centeno, M.L.; Henderson, J.A.; Bethea, C.L.
Brain Res. Mol. Brain Res.
135
194-203
Different properties of the central and peripheral forms of human tryptophan hydroxylase
2005
McKinney, J.; Knappskog, P.M.; Haavik, J.
J. Neurochem.
92
311-320
Tryptophan hydroxylase-2 controls brain serotonin synthesis
2004
Zhang, X.; Beaulieu, J.M.; Sotnikova, T.D.; Gainetdinov, R.R.; Caron, M.G.
Science
305
217
Induction of dopamine biosynthesis by l-DOPA in PC12 cells: implications of L-DOPA influx and cyclic AMP
2008
Jin, C.M.; Yang, Y.J.; Huang, H.S.; Lim, S.C.; Kai, M.; Lee, M.K.
Eur. J. Pharmacol.
591
88-95
Characterization of putative tryptophan monooxygenase from Ralstonia solanacearum
2009
Kurosawa, N.; Hirata, T.; Suzuki, H.
J. Biochem.
146
23-32
BRENDA home
more
Show all BRENDA pathways known for 5,6,7,8-tetrahydropteridine
close all tables 
open all tables
top
