Ligand Prostaglandin H1

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Basic Ligand Information

Molecular Structure
Picture of Prostaglandin H1 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H34O5
Prostaglandin H1
NTAYABHEVAQSJS-BRIYLRKRSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
prostaglandin H1 + [reduced NADPH-hemoprotein reductase] + O2 = 19-hydroxy-prostaglandin H1 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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Prostaglandin H1 = Prostaglandin E1
show the reaction diagram
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prostaglandin H1 = 12(L)-hydroxy-8,10-heptadecadienoic acid + thromboxane B1
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
8,11,14-eicosatrienoic acid + O2 = prostaglandin H1 + ?
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
slight inactivation
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
26.5
-
-

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.01
-
-
0.0094
-
-
0.024
-
-

References & Links

Links to other databases for Prostaglandin H1

ChEBI
PubChem
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PubChem