Ligand lysophosphatidylserine

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Basic Ligand Information

Molecular Structure
Picture of lysophosphatidylserine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H14NO8P
lysophosphatidylserine
SHZGCJCMOBCMKK-VFUOTHLCSA-N
Synonyms:
lyso-phosphatidylserine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lyso-Phosphatidylserine + phospholipid = Phosphatidylserine + lyso-phospholipid
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phosphatidylserine + H2O = lysophosphatidylserine + fatty acid
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
required, phosphatidylserine and lysophosphatidylserine are the best activators
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stimulates PLD activity in a concentration-dependent manner and approximately 5fold and 8fold increases in CYP1A2 and CYP2E1 activities, respectively, are shown in the presence of 2 mol% of the lysophosphatidylserine when compared to a 100% phosphatidylcholine matrix. LysoPS also accompanies conformational changes in both CYP1A2 and CYP2E1 when assayed by circular dichroism
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition of enzyme form A
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weakly inhibitory
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weakly inhibitory
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.076
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References & Links

Links to other databases for lysophosphatidylserine

ChEBI
PubChem
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PubChem