Ligand Photinus luciferin

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Basic Ligand Information

Molecular Structure
Picture of Photinus luciferin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H8N2O3S2
Photinus luciferin
BJGNCJDXODQBOB-SSDOTTSWSA-N
Synonyms:
beetle D-luciferin, beetle luciferin, D-firefly luciferin, D-luciferin, Luciferin
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
show the reaction diagram
-
luciferin + O2 + ATP = oxidized luciferin + CO2 + H2O + AMP + diphosphate + hv
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (40 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
luciferin + O2 = oxidized luciferin + CO2 + hnu
show the reaction diagram
-
luciferin + O2 = oxidized luciferin + CO2 + hv
show the reaction diagram
-
luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
show the reaction diagram
-
luciferin + O2 + ATP = oxidized luciferin + CO2 + H2O + AMP + diphosphate + hv
show the reaction diagram
-
ATP + D-firefly luciferin + CoA = AMP + diphosphate + D-firefly luciferyl-CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
preparations supplemented with extra luciferin provide maximum light emission
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (29 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.85
-
-

KM Value (124 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0005
-
-

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.135
-
inhibits CoA-ligase activity with L-luciferin, IC50: 0.135 mM against 0.1 mM L-luciferin
0.135
-
at 25°C, pH not specified in the publication

References & Links

Links to other databases for Photinus luciferin

ChEBI
PubChem
ChEBI
PubChem