Ligand Arginine methyl ester

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Basic Ligand Information

Molecular Structure
Picture of Arginine methyl ester (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H16N4O2
Arginine methyl ester
ZDLDXNCMJBOYJV-YFKPBYRVSA-N
Synonyms:
arginyl methyl ester, L-Arg-OMe, L-arginine-methyl ester, L-arginine methyl ester, L-arginyl methyl ester, L-Arg methyl ester, Nalpha-L-Arg methyl ester

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + L-arginine methyl ester = ADP + Nomega-phospho-L-arginine methyl ester
show the reaction diagram
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L-Arg methyl ester + H2O = L-Arg + methanol
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ADP-ribosylarginine methyl ester + H2O = ADP-ribose + arginine methyl ester
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition of alpha-S1-casein-dependent reaction
-
1 mM, 80% inhibition
-
competitive to L-Arg
-
15% inhibition with 2 mM arginine methyl ester
-
12.5 mM, 48% inhibition
-
strong inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.5
-
inhibition of reaction with alphaS1-casein as acceptor
0.189
-
pH 7.5, 37°C

References & Links

Links to other databases for Arginine methyl ester

ChEBI
PubChem
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PubChem