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Ligand 3-aminobenzoic acid

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Basic Ligand Information

Molecular Structure
Picture of 3-aminobenzoic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H7NO2
3-aminobenzoic acid
XFDUHJPVQKIXHO-UHFFFAOYSA-N
Synonyms:
3-amino-1-benzoic acid, 3-aminobenzoate, m-Aminobenzoate, m-aminobenzoic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-formyl-m-aminobenzoic acid + H2O = formate + m-aminobenzoic acid
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-aminobenzoate + O2 + NADH = 3-amino-2-hydro-1,2-dihydroxybenzoate
show the reaction diagram
-
3-aminobenzoate + NAD(P)H + O2 = ?
show the reaction diagram
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acetyl-CoA + 3-aminobenzoic acid = CoA + N-acetyl-3-aminobenzoic acid
show the reaction diagram
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3-aminobenzoic acid + UDP-glucose = UDP + 3-aminobenzoyl-beta-D-glucoside
show the reaction diagram
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UDP-alpha-D-glucose + 3-aminobenzoic acid = ? + UDP
show the reaction diagram
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UDP-glucose + 3-aminobenzoic acid = UDP + 3-glucosylaminobenzoic acid
show the reaction diagram
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thiamine + m-aminobenzoic acid = 4-methyl-5-(2-hydroxyethyl)-thiazole + 3-[[(4-amino-2-methylpyrimidin-5-yl)methyl]amino]benzoic acid
show the reaction diagram
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ATP + 3-aminobenzoate + CoA = AMP + diphosphate + 3-aminobenzoyl-CoA
show the reaction diagram
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ATP + 3-aminobenzoate + CoA = AMP + diphosphate + 3-aminobenzoyl-CoA
show the reaction diagram
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ATP + 3-aminobenzoate = diphosphate + (3-aminobenzoyl)adenylate
show the reaction diagram
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ATP + 3-aminobenzoate + a holo-[acyl-carrier protein] = 3-aminobenzoyl-[acyl-carrier protein] + AMP + diphosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-phospho-pyridoxyl-3-aminobenzoate + H2O + O2 = pyridoxal 5'-phosphate + 3-aminobenzoate + H2O2
show the reaction diagram
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1-(3'-carboxyphenylazo)-2-naphthol + NAD(P)H = 3-amino-1-benzoic acid + NAD(P)+ + 1-amino-2-hydroxynaphthalene
show the reaction diagram
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3-phenylacetamidobenzoic acid + H2O = phenylacetate + 3-aminobenzoic acid
show the reaction diagram
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N-formyl-m-aminobenzoic acid + H2O = formate + m-aminobenzoic acid
show the reaction diagram
-
3-aminobenzonitrile + H2O = 3-aminobenzoic acid + NH3
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.8 mM, about 45% inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (23 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.8
-
pH 8.0, 31°C, recombinant wild-type enzyme

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.404
-
pH 7.0, 30°C, with 4-coumaroyl-CoA
12.5
-
-
0.4882
-
-
37
-
-
0.174
-
pH 8.0, 31°C, recombinant wild-type enzyme

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.6
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
10
-
IC50 above 10 mM, at pH 8.3 and 37°C

References & Links

Links to other databases for 3-aminobenzoic acid

ChEBI
PubChem
ChEBI
PubChem