print visible entries

print all entries

Ligand 2-acyl-sn-glycerol 3-phosphate

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.52

acyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

486355

-

In Vivo Product in Enzyme-catalyzed Reactions (5 results)

top print hide

Show Natural Product (5 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.15

acyl-CoA + sn-glycerol 3-phosphate = CoA + 2-acyl-sn-glycerol 3-phosphate

0

-

2.3.1.198

acyl-CoA + sn-glycerol 3-phosphate = CoA + 2-acyl-sn-glycerol 3-phosphate

0

-

3.1.1.118

a 1,2-diacyl-sn-glycerol 3-phosphate + H2O = a 2-acyl-sn-glycerol 3-phosphate + a fatty acid

0

-

3.1.1.32

phosphatidic acid + H2O = 2-acyl-lysophosphatidic acid + a carboxylate

0, 652226, 652486, 652297

-

3.1.1.32

phosphatidic acid + H2O = 2-acylglycerophosphatidic acid + a carboxylate

650008

-

3.1.1.32

2 entries

Substrate in Enzyme-catalyzed Reactions (10 results)

top print hide

Show Substrate (10 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.51

acyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + ?

486373, 487192, 487184, 486375

-

2.3.1.52

acyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

486355

-

2.3.1.52

arachidonoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-arachidonoyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

lauroyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-lauroyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

linoleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-linoleoyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

myristoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-myristoyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate

487212, 486375, 486337, 486643, 486355

-

2.3.1.52

palmitoleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-palmitoleoyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate

487212, 486375, 486355, 486337, 486643

-

2.3.1.52

stearoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-stearoyl-2-acyl-sn-glycerol 3-phosphate

486643

-

2.3.1.52

9 entries

Product in Enzyme-catalyzed Reactions (8 results)

top print hide

Show Product (8 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.15

acyl-CoA + sn-glycerol 3-phosphate = CoA + 2-acyl-sn-glycerol 3-phosphate

0

-

2.3.1.158

palmitoyl phospholipid + dioleoylglycerol = 1-lysophospholipid + 1-palmitoyl-2,3-dioleoyl-sn-glycerol

0

-

2.3.1.198

acyl-CoA + sn-glycerol 3-phosphate = CoA + 2-acyl-sn-glycerol 3-phosphate

0

-

3.1.1.118

a 1,2-diacyl-sn-glycerol 3-phosphate + H2O = a 2-acyl-sn-glycerol 3-phosphate + a fatty acid

0

-

3.1.1.32

phosphatidic acid + H2O = 2-acyl-lysophosphatidic acid + a carboxylate

0, 652226, 652486, 652297

-

3.1.1.32

phosphatidic acid + H2O = 2-acylglycerol-3-phosphate + a carboxylate

0

-

3.1.1.32

phosphatidic acid + H2O = 2-acylglycerophosphatidic acid + a carboxylate

0, 650008

-

3.1.1.32

phosphatidic acid + H2O = 2-acyllysophosphatidic acid + a carboxylate

0

-

3.1.1.32

4 entries

Enzyme Kinetic Parameters

References & Links

Literature References (12)

top print hide

Show Reference (12 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

486337

-

Comparison of certain properties of membrane bound and solubilized acetyltransferase activities of plant microsomes

1990

Frentzen, M.

Plant Sci.

69

39-48

486355

402117

Studies on lipid metabolism in Tetrahymena pyriformis: properties of acyltransferase systems

1977

Okuyama, H.; Yamada, K.; Kameyama, Y.; Ikezawa, H.; Fukushima, H.; Nozawa, Y.

Arch. Biochem. Biophys.

178

319-326

486373

4352195

Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme A: monoacylglycerophosphate acyltransferases in Escherichia coli

1973

Okuyama, H.; Wakil, S.J.

J. Biol. Chem.

248

5197-5205

486375

334080

Acyltransferase systems involved in phospholipid metabolism in Saccharomyces cerevisiae

1977

Yamada, K.; Okuyama, H.; Endo, Y.; Ikezawa, H.

Arch. Biochem. Biophys.

183

281-289

486643

4774123

Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes

1973

Yamashita, S.; Hosaka, K.; Numa, S.

Eur. J. Biochem.

38

25-31

487184

24186288

Substrate specificities of the membrane-bound and partially purified microsomal acyl-CoA:1-acylglycerol-3-phosphate acyltransferase from etiolated shoots of Pisum sativum (L.)

1991

Hares, W.; Frentzen, M.

Planta

185

124-131

487192

6491529

Properties of acyl-coenzyme A:1-acylglycerophosphate acyltransferase and lipases in porcine erythrocyte membranes

1984

Mizuno, M.; Sugiura, Y.; Okuyama, H.

J. Lipid Res.

25

843-850

487212

7396849

Fatty acid specificities of microsomal acyltransferases esterifying positions-1 and -2 of acylglycerols in mammary glands from lactating rats

1980

Cooper, S.M.; Grigor, M.R.

Biochem. J.

187

289-295

650008

10924127

Membrane lipids have multiple effects on interfacial catalysis by a phosphatidic acid-preferring phospholipase A1 from bovine testis

2000

Lin, Q.; Higgs, H.N.; Glomset, J.A.

Biochemistry

39

9335-9344

652226

11788596

A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125

2002

Nakajima, K.; Sonoda, H.; Mizoguchi, T.; Aoki, J.; Arai, H.; Nagahama, M.; Tagaya, M.; Tani, K.

J. Biol. Chem.

277

11329-11335

652297

12063250

A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid

2002

Sonoda, H.; Aoki, J.; Hiramatsu, T.; Ishida, M.; Bandoh, K.; Nagai, Y.; Taguchi, R.; Inoue, K.; Arai, H.

J. Biol. Chem.

277

34254-34263

652486

12963729

Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta

2003

Hiramatsu, T.; Sonoda, H.; Takanezawa, Y.; Morikawa, R.; Ishida, M.; Kasahara, K.; Sanai, Y.; Taguchi, R.; Aoki, J.; Arai, H.

J. Biol. Chem.

278

49438-49447

Links to other databases for 2-acyl-sn-glycerol 3-phosphate

top print hide

Show Links (1 entry)