Ligand 11alpha-hydroxyprogesterone

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Basic Ligand Information

Molecular Structure
Picture of 11alpha-hydroxyprogesterone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H30O3
11alpha-hydroxyprogesterone
BFZHCUBIASXHPK-QJSKAATBSA-N
Synonyms:
11alpha-hydroxy-pregn-4-ene-3,20-dione, 11alpha-hydroxy-progesterone
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
11alpha-hydroxy-pregn-4-ene-3,20-dione + ? = pregn-4-ene-3,11,20-trione + ?
show the reaction diagram
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11alpha-hydroxyprogesterone + UDP-glucuronate = UDP + 11alpha-hydroxyprogesterone-11-O-alpha-D-glucuronate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
11alpha-hydroxy-pregn-4-ene-3,20-dione + ? = pregn-4-ene-3,11,20-trione + ?
show the reaction diagram
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11alpha-hydroxyprogesterone + NADPH + O2 = 6beta,11alpha-dihydroxyprogesterone
show the reaction diagram
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11alpha-hydroxyprogesterone + acceptor = 11alpha-hydroxy-1,4-pregnene-3,20-dione + reduced acceptor
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
progesterone + reduced adrenodoxin + O2 = 15beta-hydroxy-progesterone + 11alpha-hydroxy-progesterone + oxidized adrenodoxin + H2O
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
induced by
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Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0196
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i.e. 4-pregnene-11alpha-ol-3,20-dione, 11beta-hydroxy-4-androstene-3,17-dione, 4-estren-3,17-dione

References & Links

Links to other databases for 11alpha-hydroxyprogesterone

ChEBI
PubChem
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PubChem