Ligand 1-monooleoylglycerol

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Basic Ligand Information

Molecular Structure
Picture of 1-monooleoylglycerol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H40O4
1-monooleoylglycerol
RZRNAYUHWVFMIP-KTKRTIGZSA-N
Synonyms:
1(2)-monoolein, 1(3)-monoolein, 1(3)-monooleoylglycerol, 1-mono-oleyl-rac-glycerol, 1-monoolein, 1-monooleoylglycerol ester, 1-monooleyl glycerol, 1-olein, 1-oleoyl-glycerol, 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oleoylglycerol, mono-oleoyl-glycerol, monoolein, monooleoylglycerol, oleoyl glycerol, rac-1(3)-oleoylglycerol, rac-1-monooleoylglycerol ether, rac-1-oleoylglycerol, sn-1-monooleoylglycerol
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-monooleoylglycerol + H2O = glycerol + oleate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (31 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
monoolein + NADH + H+ + O2 = 18-hydroxyoctadec-9-enoic acid 2,3-dihydroxypropyl ester + NAD+ + H2O
show the reaction diagram
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palmitoyl-CoA + 1-monoolein = CoA + ?
show the reaction diagram
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palmitoyl-CoA + monooleoylglycerol = ?
show the reaction diagram
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ATP + 1-monoolein = ADP + 1-oleoylglycerol 3-phosphate
show the reaction diagram
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monoolein + H2O = glycerol + oleic acid
show the reaction diagram
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1(3)-monoolein + H2O = ?
show the reaction diagram
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1(3)-monoolein + H2O = ?
show the reaction diagram
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monooleoylglycerol + H2O = oleic acid + glycerol
show the reaction diagram
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1-monooleoylglycerol + H2O = glycerol + oleate
show the reaction diagram
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monoolein + H2O = oleate + glycerol
show the reaction diagram
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monoolein + H2O = oleate + glycerol
show the reaction diagram
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oleoyl glycerol = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
diolein + H2O = monooleoylglycerol + oleic acid
show the reaction diagram
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glycerol + oleic acid = monoolein + H2O
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
significant stimulation
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activates
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2 mM, 76% inhibition
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0.5 mM significantly reduce the P-glycoprotein protein expression, 0.1 mM of 1-monoolein does not have any significant effect on the expression of P-glycoprotein
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Enzyme Kinetic Parameters

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
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Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 1-monooleoylglycerol

ChEBI
PubChem
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PubChem