Ligand (1'S)-averantin

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Basic Ligand Information

Molecular Structure
Picture of (1'S)-averantin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H20O7
(1'S)-averantin
WGPOPPKSQRZUTP-LBPRGKRZSA-N
Synonyms:
(1) (1'S)-averantin, (2) (1'S)-averantin, 5'-hydroxyaverantin


Show all pahtways known for Show all BRENDA pathways known for (1'S)-averantin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
5'-hydroxyaverantin + NADP+ = (1'S)-5'-oxoaverantin + NADPH + H+
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
norsolorinic acid + NADPH + H+ = (1'S)-averantin + NADP+
-
-
show the reaction diagram
averantin + [reduced NADPH-hemoprotein reductase] + O2 = 5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
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Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
(1'S)-averantin + NADP+ = norsolorinic acid + NADPH + H+
-
show the reaction diagram
5'-hydroxyaverantin + NADP+ = (1'S)-5'-oxoaverantin + NADPH + H+
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
norsolorinic acid + NADPH + H+ = (1'S)-averantin + NADP+
-
-
show the reaction diagram
averantin + [reduced NADPH-hemoprotein reductase] + O2 = 5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
-

Enzyme Kinetic Parameters

KM Value (3 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
in 30 mM potassium phosphate buffer (pH 7.5), at 37°C
0.0426
-
in 60 mM potassium phosphate buffer (pH 7.5), at 30°C
0.083
-
pH 7.5, 37°C
0.0426
-

References & Links

Links to other databases for (1'S)-averantin

ChEBI
PubChem
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PubChem