Ligand dTDP-4-dehydro-6-deoxy-D-glucose

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Basic Ligand Information

Molecular Structure
Picture of dTDP-4-dehydro-6-deoxy-D-glucose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H24N2O15P2
dTDP-4-dehydro-6-deoxy-D-glucose
PSXWNITXWWECNY-UCBTUHGZSA-N
Synonyms:
4,6-Dideoxy-4-oxo-dTDP-D-glucose, dTDP-4-dehydro-6-deoxy-alpha-D-galactose, dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose, dTDP-4-dehydro-6-deoxy-alpha-D-glucose, dTDP-4-dehydro-6-deoxy-D-galactose, dTDP-4-keto-6-deoxy-D-glucose, dTDP-4-keto-6-deoxygalactose, dTDP-4-keto-6-deoxyglucose, dTDP-4-oxo-6-deoxy-D-glucose, dTDP-6-deoxy-D-xylo-4-hexulose, TDP-4-dehydro-6-deoxy-D-glucose, TDP-4-keto-6-deoxy-D-glucose, TDP-6-deoxy-D-xylo-hexopyranosid-4-ulose


Show all pahtways known for Show all BRENDA pathways known for dTDP-4-dehydro-6-deoxy-D-glucose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate = dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
show the reaction diagram
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dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O
show the reaction diagram
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dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-beta-D-gulose
show the reaction diagram
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dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-glucose
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-D-glucose + NADPH
show the reaction diagram
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dTDP-alpha-D-fucopyranose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H+
show the reaction diagram
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dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate
show the reaction diagram
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dTDP-D-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (26 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate = dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
show the reaction diagram
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dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O
show the reaction diagram
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dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-beta-D-gulose
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-D-glucose + NADPH
show the reaction diagram
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dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (15 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
43.5
-
-
2.78
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37°C, pH 7.4
0.38
-
pH 7.5, 25°C
0.1
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pH 7.5, 25°C

KM Value (21 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0169
-
pH 8.5, 30°C
0.097
-
sequential reaction mechnism
0.38
-
37°C, pH 7.4
0.027
-
pH 7.5, 25°C

References & Links

Links to other databases for dTDP-4-dehydro-6-deoxy-D-glucose

ChEBI
PubChem
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PubChem