Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Characterization of Drosophila melanogaster JmjC+N histone demethylases
2008
Lloret-Llinares, M.; Carre, C.; Vaquero, A.; de Olano, N.; Azorin, F.
Nucleic Acids Res.
36
2852-2863
Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene
2009
Ishimura, A.; Terashima, M.; Kimura, H.; Akagi, K.; Suzuki, Y.; Sugano, S.; Suzuki, T.
Biochem. Biophys. Res. Commun.
389
366-371
Identification of non-histone substrates for JMJD2A-C histone demethylases
2009
Ponnaluri, V.; Vavilala, D.; Putty, S.; Gutheil, W.; Mukherji, M.
Biochem. Biophys. Res. Commun.
390
280-284
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
2009
Brasacchio, D.; Okabe, J.; Tikellis, C.; Balcerczyk, A.; George, P.; Baker, E.K.; Calkin, A.C.; Brownlee, M.; Cooper, M.E.; El-Osta, A.
Diabetes
58
1229-1236
Histone lysine methyltransferases and demethylases in Plasmodium falciparum
2008
Cui, L.; Fan, Q.; Cui, L.; Miao, J.
Int. J. Parasitol.
38
1083-1097
Rice jmjC domain-containing gene JMJ706 encodes H3K9 demethylase required for floral organ development
2008
Sun, Q.; Zhou, D.
Proc. Natl. Acad. Sci. USA
105
13679-13684
Epigenetic regulation: methylation of histone and non-histone proteins
2009
Lan, F.; Shi, Y.
Sci. China C Life Sci.
52
311-322
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
2008
Perillo, B.; Ombra, M.; Bertoni, A.; Cuozzo, C.; Sacchetti, S.; Sasso, A.; Chiariotti, L.; Malorni, A.; Abbondanza, C.; Avvedimento, E.
Science
319
202-206
Features of the PHF8/KIAA1718 histone demethylase
2010
Suganuma, T.; Workman, J.
Cell Res.
20
861-862
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6
2011
Toyokawa, G.; Cho, H.; Iwai, Y.; Yoshimatsu, M.; Takawa, M.; Hayami, S.; Maejima, K.; Shimizu, N.; Tanaka, H.; Tsunoda, T.; Field, H.; Kelly, J.; Neal, D.; Ponder, B.; Maehara, Y.; Nakamura, Y.; Hamamoto, R.
Cancer Prev. Res. (Phila)
4
2051-2061
Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family
2011
Hillringhaus, L.; Yue, W.W.; Rose, N.R.; Ng, S.S.; Gileadi, C.; Loenarz, C.; Bello, S.H.; Bray, J.E.; Schofield, C.J.; Oppermann, U.
J. Biol. Chem.
286
41616-41625
Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase
2013
Ipenberg, I.; Guttmann-Raviv, N.; Khoury, H.P.; Kupershmit, I.; Ayoub, N.
J. Biol. Chem.
288
14681-14687
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation
2011
Verrier, L.; Escaffit, F.; Chailleux, C.; Trouche, D.; Vandromme, M.
PLoS Genet.
7
e1001390
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
2011
Shi, L.; Sun, L.; Li, Q.; Liang, J.; Yu, W.; Yi, X.; Yang, X.; Li, Y.; Han, X.; Zhang, Y.; Xuan, C.; Yao, Z.; Shang, Y.
Proc. Natl. Acad. Sci. USA
108
7541-7546
The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations
2017
Hancock, R.L.; Masson, N.; Dunne, K.; Flashman, E.; Kawamura, A.
ACS Chem. Biol.
12
1011-1019
Histone demethylase JMJD1C regulates esophageal cancer proliferation Via YAP1 signaling
2017
Cai, Y.; Fu, X.; Deng, Y.
Am. J. Cancer Res.
7
115-124
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1beta-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes
2014
El Mansouri, F.; Nebbaki, S.; Kapoor, M.; Afif, H.; Martel-Pelletier, J.; Pelletier, J.; Benderdour, M.; Fahmi, H.
Arthritis Res. Ther.
16
R113
The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer
2014
Shen, Y.; Pan, X.; Zhao, H.
Biochem. Biophys. Res. Commun.
451
119-125
KDM7A histone demethylase mediates TNF-alpha-induced ICAM1 protein upregulation by modulating lysosomal activity
2016
Choi, J.Y.; Jo, S.A.
Biochem. Biophys. Res. Commun.
478
1355-1362
Lysine-specific demethylase 1A (KDM1A/LSD1) product recognition and kinetic analysis of full-length histones
2016
Burg, J.M.; Gonzalez, J.J.; Maksimchuk, K.R.; McCafferty, D.G.
Biochemistry
55
1652-1662
Histone demethylase PHF8 regulates hypoxia signaling through HIF1alpha and H3K4me3
2017
Maina, P.K.; Shao, P.; Jia, X.; Liu, Q.; Umesalma, S.; Marin, M.; Long, D.; Concepcion-Roman, S.; Qi, H.H.
Biochim. Biophys. Acta
1860
1002-1012
Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1
2017
Amano, Y.; Kikuchi, M.; Sato, S.; Yokoyama, S.; Umehara, T.; Umezawa, N.; Higuchi, T.
Bioorg. Med. Chem.
25
2617-2624
4-biphenylalanine- and 3-phenyltyrosine-derived hydroxamic acids as inhibitors of the JumonjiC-domain-containing histone demethylase KDM4A
2016
Morera, L.; Roatsch, M.; Fuerst, M.C.; Hoffmann, I.; Senger, J.; Hau, M.; Franz, H.; Schuele, R.; Heinrich, M.R.; Jung, M.
ChemMedChem
11
2063-2083
The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L
2016
Pedanou, V.E.; Gobeil, S.; Tabaries, S.; Simone, T.M.; Zhu, L.J.; Siegel, P.M.; Green, M.R.
eLife
5
e16844
Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development
2016
Pedersen, M.T.; Kooistra, S.M.; Radzisheuskaya, A.; Laugesen, A.; Johansen, J.V.; Hayward, D.G.; Nilsson, J.; Agger, K.; Helin, K.
EMBO J.
35
1550-1564
Hairless is a histone H3K9 demethylase
2014
Liu, L.; Kim, H.; Casta, A.; Kobayashi, Y.; Shapiro, L.; Christiano, A.
FASEB J.
28
1534-1542
Histone H3K9 demethylase JMJD1A modulates hepatic stellate cells activation and liver fibrosis by epigenetically regulating peroxisome proliferator-activated receptor gamma
2015
Jiang, Y.; Wang, S.; Zhao, Y.; Lin, C.; Zhong, F.; Jin, L.; He, F.; Wang, H.
FASEB J.
29
1830-1841
JMJ24 antagonizes histone H3K9 demethylase IBM1/JMJ25 function and interacts with RNAi pathways for gene silencing
2017
Audonnet, L.; Shen, Y.; Zhou, D.
Gene Expr. Patterns
25-26
1-7
The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function
2015
Liu, Z.; Chen, X.; Zhou, S.; Liao, L.; Jiang, R.; Xu, J.
Int. J. Biol. Sci.
11
494-507
Lysine-specific demethylase-1 (LSD1) depletion disrupts monogenic and monoallelic odorant receptor (OR) expression in an olfactory neuronal cell line
2017
Vyas, R.N.; Meredith, D.; Lane, R.P.
Mol. Cell. Neurosci.
82
1-11
KdmA, a histone H3 demethylase with bipartite function, differentially regulates primary and secondary metabolism in Aspergillus nidulans
2015
Gacek-Matthews, A.; Noble, L.M.; Gruber, C.; Berger, H.; Sulyok, M.; Marcos, A.T.; Strauss, J.; Andrianopoulos, A.
Mol. Microbiol.
96
839-860
KDM4C, a H3K9me3 histone demethylase, is involved in the maintenance of human ESCC-initiating cells by epigenetically enhancing SOX2 expression
2016
Yuan, X.; Kong, J.; Ma, Z.; Li, N.; Jia, R.; Liu, Y.; Zhou, F.; Zhan, Q.; Liu, G.; Gao, S.
Neoplasia
18
594-609
RNA-dependent chromatin localization of KDM4D lysine demethylase promotes H3K9me3 demethylation
2014
Zoabi, M.; Nadar-Ponniah, P.T.; Khoury-Haddad, H.; Usaj, M.; Budowski-Tal, I.; Haran, T.; Henn, A.; Mandel-Gutfreund, Y.; Ayoub, N.
Nucleic Acids Res.
42
13026-13038
KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis
2014
Kupershmit, I.; Khoury-Haddad, H.; Awwad, S.W.; Guttmann-Raviv, N.; Ayoub, N.
Nucleic Acids Res.
42
6168-6182
HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372
2017
An, J.; Xu, J.; Li, J.; Jia, S.; Li, X.; Lu, Y.; Yang, Y.; Lin, Z.; Xin, X.; Wu, M.; Zheng, Q.; Pu, H.; Gui, X.; Li, T.; Lu, D.
Oncotarget
8
49093-49109
The histone demethylase Kdm3a is required for normal epithelial proliferation ductal elongation and tumor growth in the mouse mammary gland
2017
Qin, L.; Xu, Y.; Yu, X.; Toneff, M.; Li, D.; Liao, L.; Martinez, J.; Li, Y.; Xu, J.
Oncotarget
8
84761-84775
JMJ27, an Arabidopsis H3K9 histone demethylase, modulates defense against Pseudomonas syringae and flowering time
2017
Dutta, A.; Choudhary, P.; Caruana, J.; Raina, R.
Plant J.
91
1015-1028
The histone demethylase PHF8 is essential for endothelial cell migration
2016
Gu, L.; Hitzel, J.; Moll, F.; Kruse, C.; Malik, R.A.; Preussner, J.; Looso, M.; Leisegang, M.S.; Steinhilber, D.; Brandes, R.P.; Fork, C.
PLoS ONE
11
e0146645
Histone H3K9 demethylase JMJD2B activates adipogenesis by regulating H3K9 methylation on PPARgamma and C/EBPalpha during adipogenesis
2017
Jang, M.K.; Kim, J.H.; Jung, M.H.
PLoS ONE
12
e0168185
Cadmium induces histone H3 lysine methylation by inhibiting histone demethylase activity
2015
Xiao, C.; Liu, Y.; Xie, C.; Tu, W.; Xia, Y.; Costa, M.; Zhou, X.
Toxicol. Sci.
145
80-89
The H3K9 methyltransferase G9a represses E-cadherin and is associated with myometrial invasion in endometrial cancer
2015
Hsiao, S.M.; Chen, M.W.; Chen, C.A.; Chien, M.H.; Hua, K.T.; Hsiao, M.; Kuo, M.L.; Wei, L.H.
Ann. Surg. Oncol.
22
S1556-S1565
Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A
2008
Mimasu, S.; Sengoku, T.; Fukuzawa, S.; Umehara, T.; Yokoyama, S.
Biochem. Biophys. Res. Commun.
366
15-22
Identification of non-histone substrates for JMJD2A-C histone demethylases
2009
Ponnaluri, V.; Vavilala, D.; Putty, S.; Gutheil, W.; Mukherji, M.
Biochem. Biophys. Res. Commun.
390
280-284
-
Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer
2011
Li, W.; Zhao, L.; Zang, W.; Liu, Z.; Chen, L.; Liu, T.; Xu, D.; Jia, J.
Biochem. Biophys. Res. Commun.
416
372-378
Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components
2012
Janzer, A.; Lim, S.; Fronhoffs, F.; Niazy, N.; Buettner, R.; Kirfel, J.
Biochem. Biophys. Res. Commun.
421
665-670
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1
2009
Gaweska, H.; Henderson Pozzi, M.; Schmidt, D.M.; McCafferty, D.G.; Fitzpatrick, P.F.
Biochemistry
48
5440-5445
Histone demethylase LSD1 is a folate-binding protein
2011
Luka, Z.; Moss, F.; Loukachevitch, L.V.; Bornhop, D.J.; Wagner, C.
Biochemistry
50
4750-4756
Histone modifying enzymes structures, mechanisms, and specificities
2009
Marmorstein, R.; Trievel, R.C.
Biochim. Biophys. Acta
1789
58-68
Histone H3 lysine 4 monomethylation (H3K4me1) and H3 lysine 9 monomethylation (H3K9me1) distribution and their association in regulating gene expression under hyperglycaemic/hyperinsulinemic conditions in 3T3 cells
2012
Gupta, J.; Kumar, S.; Li, J.; Krishna Murthy Karuturi, R.; Tikoo, K.
Biochimie
94
2656-2664
The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility
2011
Iwamori, N.; Zhao, M.; Meistrich, M.L.; Matzuk, M.M.
Biol. Reprod.
84
1225-1234
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma implications for therapy
2009
Schulte, J.H.; Lim, S.; Schramm, A.; Friedrichs, N.; Koster, J.; Versteeg, R.; Ora, I.; Pajtler, K.; Klein-Hitpass, L.; Kuhfittig-Kulle, S.; Metzger, E.; Schuele, R.; Eggert, A.; Buettner, R.; Kirfel, J.
Cancer Res.
69
2065-2071
Alterations of histone modifications by cobalt compounds
2009
Li, Q.; Ke, Q.; Costa, M.
Carcinogenesis
30
1243-1251
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
2006
Yamane, K.; Toumazou, C.; Tsukada, Y.; Erdjument-Bromage, H.; Tempst, P.; Wong, J.; Zhang, Y.
Cell
125
483-95
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors
2013
Black, J.C.; Manning, A.L.; Van Rechem, C.; Kim, J.; Ladd, B.; Cho, J.; Pineda, C.M.; Murphy, N.; Daniels, D.L.; Montagna, C.; Lewis, P.W.; Glass, K.; Allis, C.D.; Dyson, N.J.; Getz, G.; Whetstine, J.R.
Cell
154
541-555
Histone methyltransferase G9a protects against acute liver injury through GSTP1
2019
Zhang, Y.; Xue, W.; Zhang, W.; Yuan, Y.; Zhu, X.; Wang, Q.; Wei, Y.; Yang, D.; Yang, C.; Chen, Y.; Sun, Y.; Wang, S.; Huang, K.; Zheng, L.
Cell Death Differ.
27
1243-1258
Histone H3K9 methyltransferase G9a in oocytes is essential for preimplantation development but dispensable for CG methylation protection
2019
Au Yeung, W.K.; BrindAmour, J.; Hatano, Y.; Yamagata, K.; Feil, R.; Lorincz, M.C.; Tachibana, M.; Shinkai, Y.; Sasaki, H.
Cell Rep.
27
282-293.e4
PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis
2010
Zhu, Z.; Wang, Y.; Li, X.; Wang, Y.; Xu, L.; Wang, X.; Sun, T.; Dong, X.; Chen, L.; Mao, H.; Yu, Y.; Li, J.; Chen, P.; Chen, C.
Cell Res.
20
794-801
The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation
2010
Qiu, J.; Shi, G.; Jia, Y.; Li, J.; Wu, M.; Li, J.; Dong, S.; Wong, J.
Cell Res.
20
908-18
Histone methyltransferase G9a is required for cardiomyocyte homeostasis and hypertrophy
2017
Papait, R.; Serio, S.; Pagiatakis, C.; Rusconi, F.; Carullo, P.; Mazzola, M.; Salvarani, N.; Miragoli, M.; Condorelli, G.
Circulation
136
1233-1246
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
2009
Huang, Y.; Stewart, T.M.; Wu, Y.; Baylin, S.B.; Marton, L.J.; Perkins, B.; Jones, R.J.; Woster, P.M.; Casero, R.A.
Clin. Cancer Res.
15
7217-7228
KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis
2017
Lin, H.; Zhu, X.; Chen, G.; Song, L.; Gao, L.; Khand, A.; Chen, Y.; Lin, G.; Tao, Q.
Development
144
3674-3685
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
2009
Brasacchio, D.; Okabe, J.; Tikellis, C.; Balcerczyk, A.; George, P.; Baker, E.K.; Calkin, A.C.; Brownlee, M.; Cooper, M.E.; El-Osta, A.
Diabetes
58
1229-1236
Functional role of G9a histone methyltransferase in cancer
2015
Casciello, F.; Windloch, K.; Gannon, F.; Lee, J.S.
Front. Immunol.
6
487
Histone H3 lysine 9 methyltransferase DIM5 is required for the development and virulence of Botrytis cinerea
2016
Zhang, X.; Liu, X.; Zhao, Y.; Cheng, J.; Xie, J.; Fu, Y.; Jiang, D.; Chen, T.
Front. Microbiol.
7
1289
The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila
2009
Lorbeck, M.T.; Singh, N.; Zervos, A.; Dhatta, M.; Lapchenko, M.; Yang, C.; Elefant, F.
Gene
450
8-17
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
2007
Loh, Y.; Zhang, W.; Chen, X.; George, J.; Ng, H.
Genes Dev.
21
2545-2557
Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase
2019
Jang, S.; Kang, C.; Yang, H.S.; Jung, T.; Hebert, H.; Chung, K.Y.; Kim, S.J.; Hohng, S.; Song, J.J.
Genes Dev.
33
620-625
Histone H3 methyltransferase Suv39h1 prevents myogenic terminal differentiation by repressing MEF2 activity in muscle cells
2016
Jin, W.; Shang, Y.; Peng, J.; Jiang, S.
Int. J. Mol. Sci.
17
1908
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
2001
Tachibana, M.; Sugimoto, K.; Fukushima, T.; Shinkai, Y.
J. Biol. Chem.
276
25309-25317
Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family
2011
Hillringhaus, L.; Yue, W.W.; Rose, N.R.; Ng, S.S.; Gileadi, C.; Loenarz, C.; Bello, S.H.; Bray, J.E.; Schofield, C.J.; Oppermann, U.
J. Biol. Chem.
286
41616-41625
Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by jumonji domain containing 1A (JMJD1A) homodimer
2013
Goda, S.; Isagawa, T.; Chikaoka, Y.; Kawamura, T.; Aburatani, H.
J. Biol. Chem.
288
36948-36956
Discovery of potent and selective inhibitors for G9a-like protein (GLP) lysine methyltransferase
2017
Xiong, Y.; Li, F.; Babault, N.; Dong, A.; Zeng, H.; Wu, H.; Chen, X.; Arrowsmith, C.H.; Brown, P.J.; Liu, J.; Vedadi, M.; Jin, J.
J. Med. Chem.
60
1876-1891
SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation
2011
Tan, M.K.; Lim, H.J.; Harper, J.W.
Mol. Cell. Biol.
31
3687-3699
A two-state activation mechanism controls the histone methyltransferase Suv39h1
2016
Mueller, M.M.; Fierz, B.; Bittova, L.; Liszczak, G.; Muir, T.W.
Nat. Chem. Biol.
12
188-193
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency
2009
Liang, Y.; Vogel, J.; Narayanan, A.; Peng, H.; Kristie, T.
Nat. Med.
15
1312-1317
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
2007
Couture, J.; Collazo, E.; Ortiz-Tello, P.A.; Brunzelle, J.S.; Trievel, R.C.
Nat. Struct. Mol. Biol.
14
689-695
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
2006
Klose, R.J.; Yamane, K.; Bae, Y.; Zhang, D.; Erdjument-Bromage, H.; Tempst, P.; Wong, J.; Zhang, Y.
Nature
442
312-316
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity
2007
Ng, S.S.; Kavanagh, K.L.; McDonough, M.A.; Butler, D.; Pilka, E.S.; Lienard, B.M.; Bray, J.E.; Savitsky, P.; Gileadi, O.; von Delft, F.; Rose, N.R.; Offer, J.; Scheinost, J.C.; Borowski, T.; Sundstrom, M.; Schofield, C.J.; Oppermann, U.
Nature
448
87-91
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
2010
Qi, H.; Sarkissian, M.; Hu, G.; Wang, Z.; Bhattacharjee, A.; Gordon, D.; Gonzales, M.; Lan, F.; Ongusaha, P.; Huarte, M.; Yaghi, N.; Lim, H.; Garcia, B.; Brizuela, L.; Zhao, K.; Roberts, T.; Shi, Y.
Nature
466
503-507
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
2010
Liu, W.; Tanasa, B.; Tyurina, O.; Zhou, T.; Gassmann, R.; Liu, W.; Ohgi, K.; Benner, C.; Garcia-Bassets, I.; Aggarwal, A.; Desai, A.; Dorrestein, P.; Glass, C.; Rosenfeld, M.
Nature
466
508-512
Functional analysis of histone demethylase Jmjd2b on lipopolysaccharide-treated murine neural stem cells (NSCs)
2013
Das, N.D.; Choi, M.R.; Jung, K.H.; Park, J.H.; Lee, H.T.; Das, A.; Kim, S.H.; Chai, Y.G.
Neurotox. Res.
23
154-165
Characterization of Drosophila melanogaster JmjC+N histone demethylases
2008
Lloret-Llinares, M.; Carre, C.; Vaquero, A.; de Olano, N.; Azorin, F.
Nucleic Acids Res.
36
2852-2863
Disordered region of H3K9 methyltransferase Clr4 binds the nucleosome and contributes to its activity
2019
Akoury, E.; Ma, G.; Demolin, S.; Broenner, C.; Zocco, M.; Cirilo, A.; Ivic, N.; Halic, M.
Nucleic Acids Res.
47
6726-6736
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation
2011
Verrier, L.; Escaffit, F.; Chailleux, C.; Trouche, D.; Vandromme, M.
PLoS Genet.
7
e1001390
Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway
2017
Ho, J.C.; Abdullah, L.N.; Pang, Q.Y.; Jha, S.; Chow, E.K.; Yang, H.; Kato, H.; Poellinger, L.; Ueda, J.; Lee, K.L.
PLoS ONE
12
e0188051
Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1
2007
Opel, M.; Lando, D.; Bonilla, C.; Trewick, S.C.; Boukaba, A.; Walfridsson, J.; Cauwood, J.; Werler, P.J.; Carr, A.M.; Kouzarides, T.; Murzina, N.V.; Allshire, R.C.; Ekwall, K.; Laue, E.D.
PLoS ONE
2
e386
Lysine-specific demethylase 1 (LSD1) is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene
2008
Zhu, Q.; Liu, C.; Ge, Z.; Fang, X.; Zhang, X.; Straat, K.; Bjoerkholm, M.; Xu, D.
PLoS ONE
3
e1446
Structural basis of the recognition of a methylated histone tail by JMJD2A
2007
Chen, Z.; Zang, J.; Kappler, J.; Hong, X.; Crawford, F.; Wang, Q.; Lan, F.; Jiang, C.; Whetstine, J.; Dai, S.; Hansen, K.; Shi, Y.; Zhang, G.
Proc. Natl. Acad. Sci. USA
104
10818-10823
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
2007
Huang, Y.; Greene, E.; Murray Stewart, T.; Goodwin, A.C.; Baylin, S.B.; Woster, P.M.; Casero, R.A.
Proc. Natl. Acad. Sci. USA
104
8023-8028
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression
2013
Young, L.C.; Hendzel, M.J.
Biochem. Cell Biol.
91
369-377
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity
2012
Pinheiro, I.; Margueron, R.; Shukeir, N.; Eisold, M.; Fritzsch, C.; Richter, F.M.; Mittler, G.; Genoud, C.; Goyama, S.; Kurokawa, M.; Son, J.; Reinberg, D.; Lachner, M.; Jenuwein, T.
Cell
150
948-960
-
The role of histone demethylase GASC1 in cancer and its therapeutic potential
2013
Holowatyj, A.; Yang, Z.
Curr. Cancer. Ther. Rev.
9
78-85
Increase in GFAP-positive astrocytes in histone demethylase GASC1/KDM4C/JMJD2C hypomorphic mutant mice
2016
Sudo, G.; Kagawa, T.; Kokubu, Y.; Inazawa, J.; Taga, T.
Genes Cells
21
218-225
JHDM3A module as an effector molecule in guide-directed modification of target chromatin
2011
Jeong, Y.S.; Park, J.S.; Ko, Y.; Kang, Y.K.
J. Biol. Chem.
286
4461-4470
An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases
2012
Upadhyay, A.K.; Rotili, D.; Han, J.W.; Hu, R.; Chang, Y.; Labella, D.; Zhang, X.; Yoon, Y.S.; Mai, A.; Cheng, X.
J. Mol. Biol.
416
319-327
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
2003
Wang, H.; An, W.; Cao, R.; Xia, L.; Erdjument-Bromage, H.; Chatton, B.; Tempst, P.; Roeder, R.G.; Zhang, L.
Mol. Cell
12
475-487
Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses
2019
Jiang, Y.; Li, C.; Wu, Q.; An, P.; Huang, L.; Wang, J.; Chen, C.; Chen, X.; Zhang, F.; Ma, L.; Liu, S.; He, H.; Xie, S.; Sun, Y.; Liu, H.; Zhan, Y.; Tao, Y.; Liu, Z.; Sun, X.; Hu, Y.; Wang, Q.; Ye, D.; Zhang, J.; Zou, S.; Wang, Y.; Wei, G.; Liu, Y.; Shi, Y.; Eugene Chin, Y.; Hao, Y.; Wang, F.; Zhang, X.
Nat. Commun.
10
2935
Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D
2012
Kim, T.D.; Oh, S.; Shin, S.; Janknecht, R.
PLoS ONE
7
e34618
Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling
2013
Tsurumi, A.; Dutta, P.; Dutta, P.; Shang, R.; Yan, S.J.; Sheng, R.; Li, W.X.
Sci. Rep.
3
2894
Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARgamma2
2018
Kim, J.H.; Jung, D.Y.; Nagappan, A.; Jung, M.H.
Sci. Rep.
8
13734