print visible entries

print all entries

Ligand isorhamnetin 3-O-glucoside

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

top print hide

Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.1.91

UDP-alpha-D-glucose + isorhamnetin = UDP + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.91

UDP-glucose + isorhamnetin = UDP + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.91

2 entries

Substrate in Enzyme-catalyzed Reactions (3 results)

top print hide

Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.115

isorhamnetin 3-O-glucoside + malonyl-CoA = CoA + isorhamnetin 3-O-glucoside 6''-O-malonylester

486144

-

2.3.1.116

malonyl-CoA + isorhamnetin 3-O-glucoside = CoA + isorhamnetin 3-O-glucoside malonylester

486144

-

2.4.2.35

UDP-D-xylose + isorhamnetin 3-O-glucoside = UDP + isorhamnetin 3-O-xylosylglucoside

488625

-

Product in Enzyme-catalyzed Reactions (7 results)

top print hide

Show Product (7 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.267

S-adenosyl-L-methionine + quercetin 3-O-beta-D-glucoside = S-adenosyl-L-homocysteine + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.115

UDP-alpha-D-glucose + isorhamnetin = UDP + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.115

UDP-glucose + isorhamnetin = UDP + isorhamnetin-3-O-beta-D-glucoside

-

-

2.4.1.91

UDPglucose + 3'-O-methylquercetin = UDP + 3'-O-methylquercetin 3-O-glucoside

-

-

2.4.1.91

UDP-alpha-D-glucose + isorhamnetin = UDP + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.91

UDP-glucose + isorhamnetin = UDP + isorhamnetin 3-O-beta-D-glucoside

-

-

2.4.1.91

UDPgalactose + isorhamnetin = UDP + isorhamnetin 3-O-glucoside

-

-

2.4.1.115

2 entries

2.4.1.91

4 entries

Inhibitor in Enzyme-catalyzed Reactions (4 results)

top print hide

Show Inhibitors (4 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.21

-

723017

-

1.14.18.1

tyrosinase inhibitors from Marrubium velutinum, flavone/flavonol glucosides

685515

-

3.1.4.39

-

715218

-

3.4.15.1

IC50: 0.4089 mM

667885

-

Enzyme Kinetic Parameters

K_M Value (1 result)

top print hide

Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.3.1.116

0.006

-

-

486144

IC₅₀ Value (1 result)

top print hide

Show IC50 Value (1 entry)

EC NUMBER

IC50 VALUE

IC50 VALUE MAXIMUM

COMMENTARY

LITERATURE

3.4.15.1

0.4089

-

IC50: 0.4089 mM

667885

References & Links

Literature References (6)

top print hide

Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

486144

7259181

Two flavonoid-specific malonyltransferases from cell suspension cultures of Petroselinum hortense: partial purification and some properties of malonyl-coenzyme A: flavone/flavonol-7-O-glycoside malonyltransferase and malonyl-coenzyme A: flavonol-3-O-glucoside malonyltransferase

1981

Matern, U.; Potts, J.R.M.; Hahlbrock, K.

Arch. Biochem. Biophys.

208

233-241

488625

-

Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development

1982

Kleinehollenhorst, G.; Behrens, H.; Pegels, G.; Strunk, N.; Wiermann, R.

Z. Naturforsch. C

37c

587-599

667885

15577228

Isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum

2004

Oh, H.; Kang, D.G.; Kwon, J.W.; Kwon, T.O.; Lee, S.Y.; Lee, D.B.; Lee, H.S.

Biol. Pharm. Bull.

27

2035-2037

685515

17287127

Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum

2007

Karioti, A.; Protopappa, A.; Megoulas, N.; Skaltsa, H.

Bioorg. Med. Chem.

15

2708-2714

715218

20415488

Evaluation of inhibitory actions of flavonols and related substances on lysophospholipase D activity of serum autotaxin by a convenient assay using a chromogenic substrate

2010

Ueda, K.; Yoshihara, M.; Nakao, M.; Tanaka, T.; Sano, S.; Fukuzawa, K.; Tokumura, A.

J. Agric. Food Chem.

58

6053-6063

723017

23456234

Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume

2013

Nakamura, S.; Fujimoto, K.; Matsumoto, T.; Ohta, T.; Ogawa, K.; Tamura, H.; Matsuda, H.; Yoshikawa, M.

J. Nat. Med.

67

799-806

Links to other databases for isorhamnetin 3-O-glucoside

top print hide

Show Links (1 entry)

ChEBI

PubChem

-