Ligand 2,4,6-trihydroxyphenylbenzylketone
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Basic Ligand Information
Molecular Structure

C14H12O4
2,4,6-trihydroxyphenylbenzylketone
SLHBRIIHMDJIBT-UHFFFAOYSA-N
2,4,6-trihydroxy-1,2-diphenyl-ethan-1-one, 2,4,6-trihydroxydeoxybenzoin, 2-phenyl-1-(2,4,6-trihydroxyphenyl)ethanone, 2-phenyl-2',4',6'-trihydroxyacetophenone, phlorobenzylketone
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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2 UDP-alpha-D-glucose + 2-phenyl-2',4',6'-trihydroxyacetophenone = 2 UDP + ?
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UDP-alpha-D-glucose + 2-phenyl-2',4',6'-trihydroxyacetophenone = UDP + ?
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Product in Enzyme-catalyzed Reactions (4 results)
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3 malonyl-CoA + phenylacetyl-CoA = 4 CoA + 4-hydroxy-6-(2-oxo-3-phenylpropyl)-2H-pyran-2-one + 6-benzyl-4-hydroxy-2H-pyran-2-one + 2-phenyl-1-(2,4,6-trihydroxyphenyl)ethanone + 3 CO2
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phenylacetyl-CoA + malonyl-CoA = 2,4,6-trihydroxyphenylbenzylketone + CoA + CO2
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3 malonyl-CoA + phenylacetyl-CoA = 4 CoA + 2,4,6-trihydroxyphenylbenzylketone + 3 CO2
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malonyl-CoA + phenylacetyl-CoA = phlorobenzylketone + CoA + Co2
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Enzyme Kinetic Parameters
References & Links
Literature References (3)
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Enzymatic Formation of Unnatural Aromatic Polyketides by Chalcone Synthase
2000
Morita, H.; Takahashi, Y.; Noguchi, H.; Abe, I.
Biochem. Biophys. Res. Commun.
279
190-195
Purification, molecular cloning and functional characterization of flavonoid C-glucosyltransferases from Fagopyrum esculentum M. (buckwheat) cotyledon
2014
Nagatomo, Y.; Usui, S.; Ito, T.; Kato, A.; Shimosaka, M.; Taguchi, G.
Plant J.
80.
437-448
C-Glycosyltransferases catalyzing the formation of di-C-glucosyl flavonoids in citrus plants
2017
Ito, T.; Fujimoto, S.; Suito, F.; Shimosaka, M.; Taguchi, G.
Plant J.
91
187-198
Links to other databases for 2,4,6-trihydroxyphenylbenzylketone