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Ligand dioleoyl-phosphatidylglycerol

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Basic Ligand Information

Molecular Structure
Picture of dioleoyl-phosphatidylglycerol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C42H79O10P
dioleoyl-phosphatidylglycerol
DSNRWDQKZIEDDB-GCMPNPAFSA-N
Synonyms:
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol), 1,2-dioleoyl-sn-glycero-3-phospho-(1-rac-glycerol), 1,2-dioleoyl-sn-glycero-3-phosphorac-(1-glycerol), 1,2-di [(cis)-9-octadecenoyl]-sn-glycero-3-phospho-(1-rac-glycerol), dioleoylphosphatidylglycerol, dioleoyl phosphatidylglycerol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CDP-dioleoylglycerol + dioleoylphosphatidylglycerol = a cardiolipin + CMP
show the reaction diagram
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1,2-dioleoyl-sn-glycero-3-phospho-(1-rac-glycerol) + H2O = 2-oleoyl-sn-glycero-3-phospho-(1-rac-glycerol) + oleate
show the reaction diagram
-
1,2-di [(cis)-9-octadecenoyl]-sn-glycero-3-phospho-(1-rac-glycerol) + H2O = ?
show the reaction diagram
-
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) + H2O = 1,2-dioleoyl-sn-glycerol + glycerol 1-phosphate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
kcat linearly increases with dioleoylphosphatidylglycerol concentration
-
stimulates the enzyme by an activating, potentially cooperative mechanism. Physiological concentrations of dioleoyl-phosphatidylglycerol influence the turnover number of the enzyme but not the interaction with UDP-glucose
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needed for full osmoregulatory activity
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.15
-
pH 8.8, 30°C

References & Links

Links to other databases for dioleoyl-phosphatidylglycerol

ChEBI
PubChem
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PubChem