Ligand TKCVIC
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Basic Ligand Information
Molecular Structure

C27H51N7O8S2
TKCVIC
RLEPUWSHIRIMLH-ACOMJQJQSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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TKCVIC + farnesyl diphosphate = diphosphate + ?
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geranylgeranyl diphosphate + Thr-Lys-Cys-Val-Ile-Cys = diphosphate + Thr-Lys-(S-geranylgeranyl)-Cys-Val-Ile-Cys
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
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0.0063
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in 50 mM Tris-HCl, 5 mM dithiothreitol, 5 mM MgCl2, and 0.01 mM ZnCl2
References & Links
Literature References (1)
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Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity
2005
Hartman, H.L.; Hicks, K.A.; Fierke, C.A.
Biochemistry
44
15314-15324
Links to other databases for TKCVIC