Ligand N-acetyl-Leu-His-Leu-Val-Leu-Arg-Leu-Arg-Gly-Gly
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Basic Ligand Information
Molecular Structure

C53H94N18O12
N-acetyl-Leu-His-Leu-Val-Leu-Arg-Leu-Arg-Gly-Gly
REOZUMYCKVCZTI-SVENKEOPSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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N-acetyl-Leu-His-Leu-Val-Leu-Arg-Leu-Arg-Gly-Gly + ascorbate + O2 = N-acetyl-Leu-Arg-Gly-hydroxyglycin + dehydroascorbate + H2O
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.018
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100 mM MES/NaOH, pH 6.0, 30 mM NaCl, 1% (v/v) ethanol, 0.001% (v/v) Triton X-100, 1 microM Cu(NO3)2, 10 mg/l catalase, 6 mM ascorbate, 8 microM N-dansyl-Tyr-Val-Gly
References & Links
Literature References (1)
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Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenase
2005
Chew, G.H.; Galloway, L.C.; McIntyre, N.R.; Schroder, L.A.; Richards, K.M.; Miller, S.A.; Wright, D.W.; Merkler, D.J.
FEBS Lett.
579
4678-4684
Links to other databases for N-acetyl-Leu-His-Leu-Val-Leu-Arg-Leu-Arg-Gly-Gly