Ligand iodonitrotetrazolium chloride

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Basic Ligand Information

Molecular Structure
Picture of iodonitrotetrazolium chloride (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H14ClIN5O2
iodonitrotetrazolium chloride
JORABGDXCIBAFL-UHFFFAOYSA-M
Synonyms:
2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-tetrazolium chloride, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloridehydrate, 2-(4-iodophenyl)-3-nitrophenyl-5-phenyltetrazolium chloride, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyl-tetrazolium chloride, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride, 2-(p-iodophenyl)-3-p-nitrophenyl-5-phenyltetrazolium chloride, 4-iodonitrotetrazolium violet, iodonitrotetrazolium, iodonitrotetrazoliumchloride, iodonitrotetrazolium violet, p-iodonitro-tetrazolium violet, p-iodonitrotetrazolium violet

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (40 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-lactate + 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride = pyruvate + ?
show the reaction diagram
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L-2-hydroxyglutarate + iodonitrotetrazolium = 2-oxoglutarate + reduced iodonitrotetrazolium
show the reaction diagram
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xanthine + iodonitrotetrazolium + H2O = urate + reduced iodonitrotetrazolium
show the reaction diagram
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octanoyl-CoA + Meldola's Blue + iodonitrotetrazolium chloride = 2-octenoyl-CoA + reduced acceptor
show the reaction diagram
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isoquinoline + 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-tetrazolium chloride + H2O = isoquinolin-1(2H)-one + reduced 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-tetrazolium chloride
show the reaction diagram
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quinaldate + 2-(4-iodophenyl)-3-nitrophenyl-5-phenyltetrazolium chloride + H2O = kynurenate + reduced 2-(4-iodophenyl)-3-nitrophenyl-5-phenyltetrazolium chloride
show the reaction diagram
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quinoline-4-carboxylate + 2-(4-iodophenyl)-3-nitrophenyl-5-phenyltetrazolium chloride + H2O = 2-oxo-1,2-dihydroquinoline-4-carboxylate + reduced 2-(4-iodophenyl)-3-nitrophenyl-5-phenyltetrazolium chloride
show the reaction diagram
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iodonitrotetrazolium + NADPH + H+ = reduced iodonitrotetrazolium + NADP+
show the reaction diagram
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DL-propargylglycine + phenazine ethosulfate + 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloridehydrate + NAD+ = ? + NADH
show the reaction diagram
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glycine + 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyl-tetrazolium chloride = HCN + CO2 + ?
show the reaction diagram
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L-proline + 4-iodonitrotetrazolium violet + H2O = DELTA1-pyrroline-5-carboxylate + reduced 4-iodonitrotetrazolium violet
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibitor of the L-glutamate:iodonitrotetrazolim oxidoreductase activity of the alpha subunit at concentrations above 0.1 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.15
-
at pH 7.1 and 30°C
1.34
-
with isoquinoline as cosubstrate
1.08
-
with quinoline as cosubstrate
0.00008
-
with quinoline-4-carboxylate as cosubstrate
0.05
-
of NADPH: acceptor oxidoreductase activity of the beta subunit of the enzyme

References & Links

Links to other databases for iodonitrotetrazolium chloride

ChEBI
PubChem
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PubChem