Ligand melibiose

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Basic Ligand Information

Molecular Structure
Picture of melibiose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H22O11
melibiose
DLRVVLDZNNYCBX-ABXHMFFYSA-N
Synonyms:
6-O-alpha-D-galactopyranosyl-D-glucopyranose, D-melibiose, D-mellibiose, Gal-alpha-(1-6)-Glc


Show all pahtways known for Show all BRENDA pathways known for melibiose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
melibiose + O2 = ? + H2O2
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Substrate in Enzyme-catalyzed Reactions (40 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
melibiose + NAD+ = ?
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melibiose + acceptor = ?
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UDP-galactose + melibiose = UDP + beta-D-galactosyl-1,3-melibiose
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melibiose + alpha-D-glucose 1-phosphate = ?
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beta-D-glucose-1-phosphate + melibiose = 6-O-alpha-D-galactopyranosyl trehalose + phosphate
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1-alpha-D-galactosyl-myo-inositol + melibiose = myo-inositol + alpha-D-galactosyl-6-O-D-galactosyl-alpha-D-glucose
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sucrose + melibiose = glucose + ?
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melibiose + H2O = D-glucose + D-galactose
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melibiose + H2O = ?
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glucose + melibiose = melibiose + D-glucose
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2.75fold activation
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Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
i.e. 6-O-alpha-D-galactosyl-alpha-D-glucose, non-competitive to raffinose, weak
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20.2% inhibition at 15 mM
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40 mM, 13% inhibition
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minimum inhibition concentration is 1.0 mM
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competitive
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (19 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
2.3
-
enzyme assay at 37C in 50 mM Tris/HCl (pH 7.0)

KM Value (60 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
57
-
25C, pH 9.0
93
-
enzyme assay at 37C in 50 mM Tris/HCl (pH 7.0)
5.2
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+ 1-alpha-D-galactosyl-myo-inositol

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for melibiose

ChEBI
PubChem
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PubChem