Ligand NG,NG-dimethyl-L-arginine

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of NG,NG-dimethyl-L-arginine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H18N4O2
NG,NG-dimethyl-L-arginine
YDGMGEXADBMOMJ-LURJTMIESA-N
Synonyms:
asymmetric dimethylarginine, dimethyl-L-arginine, dimethylarginine, N(G),N(G)-dimethyl-L-arginine, N,N-dimethyl-L-arginine, NG,NG'-dimethyl-(S)-arginine, Ng,Ng-dimethylarginine, Ngamma,Ngamma-dimethyl-L-arginine, Nomega,Nomega'-dimethyl-L-arginine, Nomega,Nomega-dimethyl-L-arginine, omega-NG,NG-asymmetric dimethylarginine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
NG,NG'-dimethyl-(S)-arginine + pyruvate = ? + L-alanine
show the reaction diagram
-
Nomega,Nomega-dimethyl-L-arginine + pyruvate = 5-(N,N-dimethylcarbamidamido)-2-oxopentanoate + alanine
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
beta-alanine as substrate
-
poor arginase 1 inhibitor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (5 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for NG,NG-dimethyl-L-arginine

ChEBI
PubChem
-
PubChem