Ligand furfural

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Basic Ligand Information

Molecular Structure
Picture of furfural (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H4O2
furfural
IEHPLRVWOHZKCS-NSCUHMNNSA-N
Synonyms:
2-formylfuran, 2-furaldehyde, 2-furancarboxaldehyde, 2-furylaldehyde, furaldehyde, furan-2-aldehyde, furan-2-carbaldehyde, furan-2-carboxaldehyde, furan-2-carboxyaldehyde, furan-carbaldehyde, furfuraldehyde, furfuryl aldehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
furan-2-carbaldehyde + cyclohexanone = ?
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (38 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
furfural + NADPH + H+ = furfuryl alcohol + NADP+
show the reaction diagram
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furaldehyde + NAD(P)H = furfuryl alcohol + NAD(P)+
show the reaction diagram
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furfural + NADH + H+ = (furan-2-yl)methanol + NAD+
show the reaction diagram
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furan-2-carboxyaldehyde + NAD+ + H2O = furan-2-formiate + NADH
show the reaction diagram
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2-furaldehyde + NAD+ + H2O = 2-furanoic acid + NADH + H+
show the reaction diagram
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furfuryl aldehyde + NAD+ + H2O = 2-furancarboxylate + NADH + H+
show the reaction diagram
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2-furaldehyde + NAD+ + H2O = furan-2-carboxylate + NADH + 2 H+
show the reaction diagram
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furfural + H2O + O2 = 2-furoic acid + H2O2
show the reaction diagram
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furfural + 2 ferricyanide + H2O = 2-furoic acid + 2 ferrocyanide + 2 H+
show the reaction diagram
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Furfural + benzyl viologen = 2-Furancarboxylic acid + reduced benzyl viologen
show the reaction diagram
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furan-2-carbaldehyde + cyclohexanone = ?
show the reaction diagram
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2-furaldehyde + pyruvate = (3E)-4-furan-2-yl-2-oxobut-3-enoate + H2O
show the reaction diagram
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cyanide + furan-2-carbaldehyde = (2S)-furan-2-yl(hydroxy)ethanenitrile
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
furfuryl alcohol + NAD+ = furfural + NADH
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
weak inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.58
-
pH 7.0, 30°C
46
-
-

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.207
-
-
4.2
-
pH 7.2, temperature not specified in the publication
0.059
-
-
0.0308
-
with benzyl viologen as cosubstrate
30.8
-
30°C, pH 7.5

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
54
-
pH 7.0, 45°C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
-999
-
IC50 value 2.3 g/l, pH 7.0, 25°C

References & Links

Links to other databases for furfural

ChEBI
PubChem
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PubChem