Ligand 2-oxooctanoate

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Basic Ligand Information

Molecular Structure
Picture of 2-oxooctanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H14O3
2-oxooctanoate
GPPUPQFYDYLTIY-UHFFFAOYSA-M
Synonyms:
2-ketooctanoic acid, 2-oxo-octanoate, 2-oxo-octanoic acid, 2-oxocaprylate, 2-oxooctanoic acid, alpha-ketooctanoic acid
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxooctanoate + NADH + H+ = 2-hydroxyoctanoate + NAD+
show the reaction diagram
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2-oxooctanoate + NADH + H+ = 2-hydroxyoctanoate + NAD+
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxyoctanoate + NAD+ = 2-oxooctanoate + NADH + H+
show the reaction diagram
-
-
2-hydroxyoctanoate + NAD+ = 2-oxooctanoate + NADH + H+
show the reaction diagram
-
-
(S)-2-hydroxyoctanoate + ferricytochrome c = 2-oxooctanoate + ferrocytochrome c
show the reaction diagram
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-
2(R)-hydroxyoctanoate + acceptor = 2-oxooctanoate + reduced acceptor
show the reaction diagram
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DL-2-aminooctanoate + 2-oxobutanoate = 2-oxooctanoate + L-2-aminobutanoate
show the reaction diagram
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-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
3.2 mM, catecholase activity: 163%
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2.5 mM, 28.5% inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1200
-
pH 7.0, temperature not specified in the publication
0.08
-
-

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.17
-
pH 7.0, 30°C
0.12
-
pH 7.0, temperature not specified in the publication
0.04
-
-
1.54
-
pH 8.3, 37°C, leucine as amino group donor

References & Links

Links to other databases for 2-oxooctanoate

ChEBI
PubChem
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PubChem