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BRENDA support

Ligand 2-dehydro-D-glucose

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Basic Ligand Information

Molecular Structure
Picture of 2-dehydro-D-glucose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H10O6
2-dehydro-D-glucose
FYWIDDXZIOQEQU-SVXWRWBYSA-N
Synonyms:
2-keto-D-glucose, 2-keto-D-mannose, D-arabino-2-hexosulose, D-glucosone

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glucose + acceptor = 2-dehydro-D-glucose + reduced acceptor
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glucosone + NADP+ = D-mannose + NADPH
show the reaction diagram
-
D-glucosone + NADPH + H+ = D-mannose + NADP+
show the reaction diagram
-
D-glucosone + NADPH + H+ = D-fructose + NADP+
show the reaction diagram
-
D-glucosone + ferricytochrome c = ? + ferrocytochrome c
show the reaction diagram
-
2-keto-D-glucose + O2 = 2,3-diketo-D-glucose + H2O2
show the reaction diagram
-
D-glucosone + O2 + H2O = ? + H2O2
show the reaction diagram
-
D-arabino-2-hexosulose + 1,4-benzoquinone = ?
show the reaction diagram
-
D-glucosone = cortalcerone + H2O
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (33 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glucose + O2 = 2-dehydro-D-glucose + H2O2
show the reaction diagram
-
D-glucose + phenazine methosulfate + O2 = D-glucosone + ?
show the reaction diagram
-
D-glucose + 2,6-dichlorophenolindophenol = 2-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
D-glucose + 2,6-dichlorophenolindophenol = 2-dehydro-D-glucose + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
5% reduction at 100 mM, 10% reduction at 200 mM, no deactivating effect determined
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
63.2
-
-
63.2
-
pH 6.5, 30°C
74.1
-
at pH 8.5 and 30°C
4.5
-
-

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
11
-
-
11
-
pH 6.5, 30°C
7.9
-
at pH 8.5 and 30°C

References & Links

Links to other databases for 2-dehydro-D-glucose

ChEBI
PubChem
ChEBI
PubChem