Ligand 1,4-dihydroxy-2-naphthoate

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Basic Ligand Information

Molecular Structure
Picture of 1,4-dihydroxy-2-naphthoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H8O4
1,4-dihydroxy-2-naphthoate
VOJUXHHACRXLTD-UHFFFAOYSA-N
Synonyms:
1,4-dihydroxy-2-naphthoic acid


Show all pahtways known for Show all BRENDA pathways known for 1,4-dihydroxy-2-naphthoate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,4-dihydroxy-2-naphthoyl-CoA + H2O = CoA + 1,4-dihydroxy-2-naphthoate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,4-dihydroxy-2-naphthoate + O2 = ?
show the reaction diagram
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S-adenosyl-L-methionine + 1,4-dihydroxy-2-naphthoic acid = S-adenosyl-L-homocysteine + 1-hydroxy-4-methoxy-2-naphthoate
show the reaction diagram

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,4-dihydroxy-2-naphthoyl-CoA + H2O = CoA + 1,4-dihydroxy-2-naphthoate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (9 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.000133
-
pH 6.0, 25°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.024
-
pH 6.0, 25°C

References & Links

Links to other databases for 1,4-dihydroxy-2-naphthoate

ChEBI
PubChem
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PubChem