Ligand N3-

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Basic Ligand Information

Molecular Structure
Picture of N3- (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H14N2O2
N3-
NEGMMKYAVYNLCG-UHFFFAOYSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
NO + N3- = N2O + ?
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates, optimal concentration is 1 mM
-
1 mM, 104% of initial activity
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Inhibitor in Enzyme-catalyzed Reactions (42 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
anion behaves as an inhibitor of the oxidase activity versus Fe2+
-
formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively
-
inhibits H2 production competitively and reversibly
-
1 mM, 87% inhibition of purified sialyltransferase-1
-
competitive to cyanate
-

Metals and Ions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
enhances the affinity for L-tryptophan for the ferric enzyme in reziprocal manner, positive cooperativity
-
retards the oxidative half-reaction
-

Enzyme Kinetic Parameters

Ki Value (15 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.8
-
-
40
-
approx. value
1.75
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
50
-
IC50: about 50 mM

References & Links

Links to other databases for N3-

ChEBI
PubChem
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PubChem