Ligand 1L-myo-inositol 1,2,3,4,6-pentakisphosphate
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Basic Ligand Information
Molecular Structure

C6H17O21P5
1L-myo-inositol 1,2,3,4,6-pentakisphosphate
CTPQAXVNYGZUAJ-QWBQGLJISA-N
1D-myo-inositol 1,2,3,4,6-pentakisphosphate, myo-inositol-1,2,3,4,6 pentakisphosphate, myo-inositol-1,2,3,4,6-pentakisphosphate, myo-inositol 1,2,3,4,6-pentakis dihydrogen phosphate, myo-inositol 1,2,3,4,6-pentakisphosphate
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + 1D-myo-inositol 1,2,3,4,6-pentakisphosphate = ADP + inositol hexakisphosphate
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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myo-inositol-1,2,3,4,5,6-hexakisphosphate + H2O = myo-inositol-1,2,3,4,6-pentakisphosphate + phosphate
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Substrate in Enzyme-catalyzed Reactions (3 results)
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ATP + 1D-myo-inositol 1,2,3,4,6-pentakisphosphate = ADP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate
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ATP + 1D-myo-inositol 1,2,3,4,6-pentakisphosphate = ADP + inositol hexakisphosphate
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myo-inositol-1,2,3,4,6 pentakisphosphate + H2O = ?
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Product in Enzyme-catalyzed Reactions (2 results)
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myo-inositol hexakisphosphate + H2O = L-myo-inositol 1,2,3,4,5-pentakisphosphate + myo-inositol 1,2,3,4,6-pentakisphosphate + myo-inositol 1,3,4,5,6-pentakisphosphate + myo-inositol 2-phosphate + D-myo-inositol 1,2-bisphosphate + L-myo-inositol 1,2-bis phosphate + L-myo-inositol 1,2,3,4-tetrakisphosphate + phosphate
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myo-inositol-1,2,3,4,5,6-hexakisphosphate + H2O = myo-inositol-1,2,3,4,6-pentakisphosphate + phosphate
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Enzyme Kinetic Parameters
References & Links
Literature References (5)
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The phytases. II. Properties of phytase fractions F1 and F2 from wheat bran and the myo-inositol phosphates produced by fraction F2
1973
Lim, P.E.; Tate, M.E.
Biochim. Biophys. Acta
302
316-328
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Localization of constitutive phytases in lily pollen and properties of the pH 8 form
1988
Baldi, B.G.; Scott, J.J.; Everard, J.D.; Loewus, F.A.
Plant Sci.
56
137-147
Specificity of hydrolysis of phytic acid by alkaline phytase from lily pollen
1994
Barrientos, L.; Scott, J.J.; Murthy, P.P.N.
Plant Physiol.
106
1489-1495
Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases
2002
Stevenson-Paulik, J.; Odom, A.R.; York, J.D.
J. Biol. Chem.
277
42711-42718
Inositol polyphosphate multikinase: metabolic architect of nuclear inositides
2008
Resnick, A.C.; Saiardi, A.
Front. Biosci.
13
856-866
Links to other databases for 1L-myo-inositol 1,2,3,4,6-pentakisphosphate