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Ligand 4-methylmorpholine N-oxide

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.7.2.3

4-methylmorpholine N-oxide + electron donor = 4-methylmorpholine + oxidized electron donor + H2O

392775, 392773, 392776

-

1.7.2.3

4-methylmorpholine-N-oxide + (ferrocytochrome c)-subunit + H+ = 4-methylmorpholine + (ferricytochrome c)-subunit + H2O

437734

-

1.7.2.3

2 entries

1.8.5.3

4-methylmorpholine N-oxide + reduced benzyl viologen + H2O = 4-methylmorpholine + oxidized benzyl viologen

712959

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (5 results)

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Show Turnover Number (5 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.7.2.3

52.2

-

tungsten-restored enzyme

392776

1.7.2.3

71.4

-

molybdenum-restored enzyme

392776

1.7.2.3

96.5

-

-

392773

1.7.2.3

109

-

-

392775

1.7.2.3

4 entries

1.8.5.3

573

-

pH 7.0, 30°C

712959

K_M Value (6 results)

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Show KM Value (6 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.7.2.3

0.00754

-

tungsten-restored enzyme

392776

1.7.2.3

0.02

-

-

392773

1.7.2.3

0.022

-

-

392775

1.7.2.3

0.0421

-

molybdenum-restored enzyme

392776

1.7.2.3

1.4

-

-

437734

1.7.2.3

5 entries

1.8.5.3

11.1

-

pH 7.0, 30°C

712959

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

392773

8639717

High substrate specificity and induction characteristics of trimethylamine N-oxide reductase of Escherichia coli

1996

Iobbi-Nivol, C.; Pommier, J.; Simala-Grant, J.; Mejean, V.; Giordano, G.

Biochim. Biophys. Acta

1294

77-82

392775

9813127

Molecular analysis of the trimethylamine N-oxide (TMAO) reductase respiratory system from a Shewanella species

1998

Dos Santos, J.; Iobbi-Nivol, C.; Couillault, C; Giordano, G.; Mejean, V.

J. Mol. Biol.

284

421-433

392776

10216869

Enzymatic and physiological properties of the tungsten-substituted molybdenum TMAO reductase from Escherichia coli

1999

Buc, J.; Santini, C.; Giordani, R.; Czjzek, M.; Wu, L.; Giordano, G.

Mol. Microbiol.

32

159-168

437734

11004177

The torYZ (yecK bisZ) operon encodes a third respiratory trimethylamine N-oxide reductase in Escherichia coli

2000

Gon, S.; Patte, J.C.; Mejean, V.; Iobbi-Nivol, C.

J. Bacteriol.

182

5779-5786

712959

8969520

Kinetic analysis and substrate specificity of Escherichia coli dimethyl sulfoxide reductase

1996

Simala-Grant, J.; Weiner, J.

Microbiology

142

3231-3239

Links to other databases for 4-methylmorpholine N-oxide

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Show Links (1 entry)

ChEBI

PubChem