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Selective inhibition of sheep kidney 11beta-hydroxysteroid dehydrogenase isoform 2 activity by 5alpha-reduced (but not 5beta) derivates of adrenocorticosteroids
1997
Latif, S.A.; Sheff, M.F.; Ribeiro, C.E.; Morris, D.J.
Steroids
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Lumenal orientation and post-translational modifications of the liver microsomal 11beta-hydroxysteroid dehydrogenase
1995
Ozols, J.
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Cloning and tissue distribution of the human 11beta-hydroxysteroid dehydrogenase type 2 enzyme
1994
Albiston, A.L.; Obeyesekere, V.R.; Smith, R.E.; Krozowski, Z.S.
Mol. Cell. Endocrinol.
105
R11-R17
Characterization of 11beta-hydroxysteroid dehydrogenase of human placenta: Evidence for the existence of two species of 11beta-hydroxysteroid dehydrogenases
1993
Lakshim, V.; Nath, N.; Muneyyirci-Delale, O.
J. Steroid Biochem. Mol. Biol.
45
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Expression and characterization of a new species of 11beta-hydroxysteroid dehydrogenase in Xenopus oocytes
1993
Naray-Fejes-Toth, A.; Rusvai, E.; Denault, D.L.; Germain, D.L.St.; Fejes-Toth, G.
Am. J. Physiol.
265
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11-beta-Hydroxysteroid dehydrogenase of rat lung: Enzyme kinetic, oxidase-reductase ration, electrolyte and trace element dependence
1993
Hundertmark, S.; Ragosch, V.; Schein, B.; Buhler, H.; Fromm, M.; Lorenz, U.; Weitzel, H.K.
Enzyme Protein
47
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Inhibition of rat renal 11beta-hydroxysteroid dehydrogenase by steroidal compounds and triterpenoids; structure/function relationship
1991
Buhler, H.; Perschel, F.H.; Hierholzer, K.
Biochim. Biophys. Acta
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Inhibitory effects of gossypol on corticosteroid 11beta-hydroxysteroid dehydrogenase from guinea pig kidney: A possible mechanism for causing hypokalemia
1991
Sang, G.W.; Lorenzo, B.; Reidenberg, M.M.
J. Steroid Biochem. Mol. Biol.
39
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Kinetic studies on rat liver 11beta-hydroxysteroid dehydrogenase
1991
Monder, C.; Lakshmi, V.; Miroff, Y.
Biochim. Biophys. Acta
1115
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Expression of 11beta-hydroxysteroid dehydrogenase using recombinant vaccinia virus
1990
Agarwal, A.K.; Tusie-Luna, M.T.; Monder, C.; White, P.C.
Mol. Endocrinol.
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Evidence for kinetically distinct forms of corticosteroid 11beta-dehydrogenase in rat liver microsomes
1989
Monder, C.; Lakshmi, V.
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Corticosteroid 11beta-hydroxysteroid dehydrogenase activities in vertebrate liver
1988
Monder, C.; Lakshmi, V.
Steroids
52
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Purification and characterization of the corticosteroid 11beta-dehydrogenase component of the rat liver 11beta-hydroxysteroid dehydrogenase complex
1988
Lakshmi, V.; Monder, C.
Endocrinology
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Metabolism of 11-oxogenated steroids. Metabolism in vitro by preparations of liver
1968
Bush, I.E.; Hunter, S.A.; Meigs, R.A.
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Regulation of 11beta-hydroxysteroid dehydrogenase enzymes in the rat kidney by estradiol
2003
Gomez-Sanchez, E.P.; Ganjam, V.; Chen, Y.J.; Liu, Y.; Zhou, M.Y.; Toroslu, C.; Romero, D.G.; Hughson, M.D.; de Rodriguez, A.; Gomez-Sanchez, C.E.
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Purification, characterization and NNK carbonyl reductase activities of 11beta-hydroxysteroid dehydrogenase type 1 from human liver: enzyme cooperativity and significance in the detoxification of a tobacco-derived carcinogen
2003
Maser, E.; Friebertshauser, J.; Volker, B.
Chem. Biol. Interact.
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Expression of 11beta-hydroxylase in rat Leydig cells
2002
Wang, G.M.; Ge, R.S.; Latif, S.A.; Morris, D.J.; Hardy, M.P.
Endocrinology
143
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Localization of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in the male reproductive tract
2003
Waddell, B.J.; Hisheh, S.; Krozowski, Z.S.; Burton, P.J.
Endocrinology
144
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Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme
2004
Schweizer, R.A.; Zurcher, M.; Balazs, Z.; Dick, B.; Odermatt, A.
J. Biol. Chem.
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Purification of full-length recombinant human and rat type 1 11beta-hydroxysteroid dehydrogenases with retained oxidoreductase activities
2002
Nobel, C.S.I.; Dunas, F.; Abrahmsen, L.B.
Protein Expr. Purif.
26
349-356
Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes
2005
Zhang, J.; Osslund, T.D.; Plant, M.H.; Clogston, C.L.; Nybo, R.E.; Xiong, F.; Delaney, J.M.; Jordan, S.R.
Biochemistry
44
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The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate
2006
Kim, K.W.; Wang, Z.; Busby, J.; Tsuruda, T.; Chen, M.; Hale, C.; Castro, V.M.; Svensson, S.; Nybo, R.; Xiong, F.; Wang, M.
Biochim. Biophys. Acta
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Evidence that the 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD1) is regulated by pentose pathway flux. Studies in rat adipocytes and microsomes
2006
McCormick, K.L.; Wang, X.; Mick, G.J.
J. Biol. Chem.
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Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes
2006
Gilmour, J.S.; Coutinho, A.E.; Cailhier, J.F.; Man, T.Y.; Clay, M.; Thomas, G.; Harris, H.J.; Mullins, J.J.; Seckl, J.R.; Savill, J.S.; Chapman, K.E.
J. Immunol.
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Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species
2005
Arampatzis, S.; Kadereit, B.; Schuster, D.; Balazs, Z.; Schweizer, R.A.; Frey, F.J.; Langer, T.; Odermatt, A.
J. Mol. Endocrinol.
35
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Endogenous selective inhibitors of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2 of adrenal origin
2005
Latif, S.A.; Pardo, H.A.; Hardy, M.P.; Morris, D.J.
Mol. Cell. Endocrinol.
243
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The selectivity of tyrosine 280 of human 11beta-hydroxysteroid dehydrogenase type 1 in inhibitor binding
2007
Kim, K.W.; Wang, Z.; Busby, J.; Tsuruda, T.; Chen, M.; Hale, C.; Castro, V.M.; Svensson, S.; Nybo, R.; Xiong, F.; Wang, M.
FEBS Lett.
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11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets
2008
Swali, A.; Walker, E.A.; Lavery, G.G.; Tomlinson, J.W.; Stewart, P.M.
Diabetologia
51
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Insulin and dexamethasone dynamically regulate adipocyte 11beta-hydroxysteroid dehydrogenase type 1
2008
Balachandran, A.; Guan, H.; Sellan, M.; van Uum, S.; Yang, K.
Endocrinology
149
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17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes
2009
Tagawa, N.; Yuda, R.; Kubota, S.; Wakabayashi, M.; Yamaguchi, Y.; Kiyonaga, D.; Mori, N.; Minamitani, E.; Masuzaki, H.; Kobayashi, Y.
J. Endocrinol.
202
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11beta-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo
2013
Mitic, T.; Shave, S.; Semjonous, N.; McNae, I.; Cobice, D.F.; Lavery, G.G.; Webster, S.P.; Hadoke, P.W.; Walker, B.R.; Andrew, R.
Biochem. Pharmacol.
86
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11beta-Hydroxysteroid dehydrogenase type 1 is expressed in neutrophils and restrains an inflammatory response in male mice
2016
Coutinho, A.E.; Kipari, T.M.; Zhang, Z.; Esteves, C.L.; Lucas, C.D.; Gilmour, J.S.; Webster, S.P.; Walker, B.R.; Hughes, J.; Savill, J.S.; Seckl, J.R.; Rossi, A.G.; Chapman, K.E.
Endocrinology
157
2928-2936
Resveratrol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rat adipose microsomes
2013
Tagawa, N.; Kubota, S.; Kato, I.; Kobayashi, Y.
J. Endocrinol.
218
311-320
11beta-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story
2015
Odermatt, A.; Klusonova, P.
J. Steroid Biochem. Mol. Biol.
151
85-92
Metabolic coupling determines the activity: comparison of 11beta-hydroxysteroid dehydrogenase 1 and its coupling between liver parenchymal cells and testicular Leydig cells
2015
Li, X.; Hu, G.; Li, X.; Wang, Y.Y.; Hu, Y.Y.; Zhou, H.; Latif, S.A.; Morris, D.J.; Chu, Y.; Zheng, Z.; Ge, R.S.
PLoS ONE
10
e0141767
Species differences of 11beta-hydroxysteroid dehydrogenase type 2 function in human and rat term placenta determined via LC-MS/MS
2016
Heussner, K.; Ruebner, M.; Huebner, H.; Rascher, W.; Menendez-Castro, C.; Hartner, A.; Fahlbusch, F.B.; Rauh, M.
Placenta
37
79-84
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis
2018
Hardy, R.S.; Fenton, C.; Croft, A.P.; Naylor, A.J.; Begum, R.; Desanti, G.; Buckley, C.D.; Lavery, G.; Cooper, M.S.; Raza, K.
J. Autoimmun.
92
104-113
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