Ligand L-glycerol-3-phosphate

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Basic Ligand Information

Molecular Structure
Picture of L-glycerol-3-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H9O6P
L-glycerol-3-phosphate
AWUCVROLDVIAJX-GSVOUGTGSA-N
Synonyms:
(R)-glyceryl phosphate, 1-sn-phosphoglycerides, 2/3-phospho-D-glycerate, D-alpha-glycerophosphate, D-glycerol 3-phosphate, D-glycerol phosphate, glycero-3-phosphatidic acid, L-2-glycerophosphate, L-alpha-glycerol 3-phosphate, L-glycerol 3-phosphate, sn-glycerol 3-phosphate[side 2]
Pathway Source
Pathways
MetaCyc
1,3-propanediol biosynthesis (engineered), anandamide biosynthesis I, anandamide biosynthesis II, cardiolipin biosynthesis I, cardiolipin biosynthesis II more

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + sn-glycerol 3-phosphate-[glycerol 3-phosphate-binding protein][side 1] = ADP + phosphate + sn-glycerol 3-phosphate[side 2] + [glycerol 3-phosphate-binding protein][side 1]
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-alpha-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH
show the reaction diagram
-
L-glycerol-3-phosphate + NAD+ = glycerone phosphate + NADH
show the reaction diagram

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glyceraldehyde 3-phosphate + NADPH = L-alpha-glycerol 3-phosphate + NADP+
show the reaction diagram
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-
glycerone phosphate + NADH = L-glycerol-3-phosphate + NAD+
show the reaction diagram
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1-oleoyl-sn-glycero-3-phosphatidic acid + glycerophosphocholine = glycero-3-phosphatidic acid + 1-oleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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ATP + H2O + sn-glycerol 3-phosphate-[glycerol 3-phosphate-binding protein][side 1] = ADP + phosphate + sn-glycerol 3-phosphate[side 2] + [glycerol 3-phosphate-binding protein][side 1]
show the reaction diagram
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-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates the decarboxylation of 5-fluoroorotate.
-

Inhibitor in Enzyme-catalyzed Reactions (22 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
i.e. L-alpha-glycerophosphate
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3D Structure of Enzyme-Ligand-Complex (PDB) (202 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.1
-
pH 6.6, 70°C
3.83
-
25°C, pH 8.0

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
17
-
pH 6.6, 70°C

References & Links

Links to other databases for L-glycerol-3-phosphate

ChEBI
PubChem
ChEBI
PubChem