Ligand Arg-4-methylcoumaryl-7-amide

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Basic Ligand Information

Molecular Structure
Picture of Arg-4-methylcoumaryl-7-amide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H21N5O3
Arg-4-methylcoumaryl-7-amide
ZSQPDAOJXSYJNP-LBPRGKRZSA-N
Synonyms:
Arg-4-methyl-coumaryl-7-amide, Arg-4-methylcoumarin-7-amide, Arg-4-methylcoumarin 7-amide, Arg-7-(4-methyl)coumarylamide, Arg-7-(4-methyl) coumarylamide, Arg-7-amido-4-methylcoumarin, Arg-AMC, Arg-methylcoumarinamide, Arg 4-methylcoumarin 7-amide, arginine-4-methylcoumarin 7-amide, arginyl-4-methylcoumarin 7-amide, arginyl-7-amido-4-methylcoumarin, H-L-Arg-NH-4-methylcoumaryl-7-amide, H2N-Arg-7-amido-4-methylcoumarin, L-Arg-4-methylcoumaryl-7-amide, L-arginine-4-methylcoumarin-7-amide, L-arginine-4-methylcoumaryl-7-amide, L-arginine-7-amido-4-methylcoumarin, L-arginine-7-amido-4-methylcoumarine, L-arginine 4-methylcoumaryl-7-amide, L-arginine 7-amido-4-methylcoumarin, L-arginyl-7-amido-4-methylcoumarin, N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (26 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Arg-7-amido-4-methylcoumarin + H2O = Arg + 7-amino-4-methylcoumarin
show the reaction diagram
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L-arginine 4-methylcoumaryl-7-amide + H2O = L-arginine + 7-amino-4-methylcoumarin
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Arg-7-amido-4-methylcoumarin + H2O = ?
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Arg-4-methyl-coumaryl-7-amide + H2O = Arg + 7-amino-4-methylcoumarin
show the reaction diagram
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Arg-4-methylcoumaryl-7-amide + H2O = Arg + 7-amino-4-methylcoumarin
show the reaction diagram
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Arg-7-amido-4-methylcoumarin + H2O = Arg + 7-amino-4-methylcoumarin
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Arg-Arg-4-methylcoumaryl-7-amide + H2O = Arg + Arg-4-methylcoumaryl-7-amide
show the reaction diagram
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tert-butyloxycarbonyl-Val-Pro-Arg-4-methylcoumarin 7-amide + H2O = tert-butyloxycarbonyl-Val-Pro + Arg-4-methylcoumarin-7-amide
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benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O = benzoyl-Arg + Arg-7-amido-4-methylcoumarin
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benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O = benzyloxycarbonyl-Arg + Arg-AMC
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benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O = benzyloxycarbonyl-Phe + Arg-4-methylcoumarin 7-amide
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (16 results)

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EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.004
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KM Value (23 results)

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EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.301
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in 250 mM Tris buffer, pH 7.5, containing 500 mM KCl and 0.1% (w/v) of bovine serum albumin, at 37°C
0.0013
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pH 7.0, 37°C
0.022
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0.05
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References & Links

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Links to other databases for Arg-4-methylcoumaryl-7-amide

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ChEBI
PubChem
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PubChem