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Ligand 1-{3-[6-(1H-indol-3-yl)-2-(1-methylpropyl)-3-oxo-3,7-dihydroimidazo[1,2-a]pyrazin-8-yl]propyl}guanidine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.13.12.6

(S)-Cypridina luciferin I + O2 = oxidized S-Cypridina luciferin I + CO2 + hv

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1.13.12.6

1-{3-[6-(1H-indol-3-yl)-2-(1-methylpropyl)-3-oxo-3,7-dihydroimidazo[1,2-a]pyrazin-8-yl]propyl}guanidine + O2 = N-[3-(3-carbamimidamidopropyl)-5-(1H-indol-3-yl)-1,4-dihydropyrazin-2-yl]-2-methylbutanamide + CO2 + hn

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1.13.12.6

DL-Cypridina luciferin + O2 = oxidized DL-Cypridina luciferin + CO2 + hv

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1.13.12.6

3 entries

Enzyme Kinetic Parameters

K_M Value (1 result)

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EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.13.12.6

0.03

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pH 7.4

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References & Links

Literature References (2)

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BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

655065

15056888

cDNA cloning and characterization of a secreted luciferase from the luminous Japanese ostracod, Cypridina noctiluca

2004

Nakajima, Y.; Kobayashi, K.; Yamagishi, K.; Enomoto, T.; Ohmiya, Y.

Biosci. Biotechnol. Biochem.

68

565-570

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Syntheses and evaluation of the bioluminescent activity of (S)-Cypridina luciferin and its analogs

2006

Wu, C.; Kawasaki, K.; Ohgiya, S.; Ohmiya, Y.

Tetrahedron Lett.

47

753-756

Links to other databases for 1-{3-[6-(1H-indol-3-yl)-2-(1-methylpropyl)-3-oxo-3,7-dihydroimidazo[1,2-a]pyrazin-8-yl]propyl}guanidine

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Show Links (1 entry)

ChEBI

PubChem

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