Ligand Phe-Ala

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Basic Ligand Information

Molecular Structure
Picture of Phe-Ala (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H16N2O3
Phe-Ala
MIDZLCFIAINOQN-WPRPVWTQSA-N
Synonyms:
L-Phe-L-Ala, L-phenylalanyl-L-alanine

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Phe-Ala-primaquine + H2O = Phe-Ala + primaquine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-Phe-L-Ala + H2O = L-Phe + L-Ala
show the reaction diagram
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Phe-Ala + H2O = Phe + Ala
show the reaction diagram
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Phe-Ala + H2O = Phe + Ala
show the reaction diagram
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Phe-Ala + H2O = Phe + Ala
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Gly-Phe-Ala + H2O = Gly + Phe-Ala
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Met-Arg-Phe-Ala + H2O = Met-Arg + Phe-Ala
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Phe-Ala-4-nitroanilide + H2O = Phe-Ala + 4-nitroaniline
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Phe-Ala-primaquine + H2O = Phe-Ala + primaquine
show the reaction diagram
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Benzyloxycarbonyl-Lys-Phe-Ala + H2O = Benzyloxycarbonyl-Lys + Phe-Ala
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Phe-Ala-Ala-Ala + H2O = Phe-Ala + Ala-Ala
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GFA + H2O = Phe-Ala + Gly
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N-acetyl-Thr-Glu-Phe-Ala + H2O = N-acetyl-Thr-Glu + Phe-Ala
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
41% inhibition at 1 mM
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at least 30% inhibition at 0.3 mM
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in the absence of dipeptides, transporter shows proton-dependent leak currents that are inhibited by Phe-Ala; in the absence of dipeptides, transporter shows proton-dependent leak currents that are inhibited by Phe-Ala, Trp-Ala, and Phe-Phe
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Enzyme Kinetic Parameters

References & Links

Links to other databases for Phe-Ala

ChEBI
PubChem
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PubChem