Ligand view of L-idonic acid (5565 - RGHNJXZEOKUKBD-SKNVOMKLSA-N)

C₆H₁₂O₇

L-idonic acid

RGHNJXZEOKUKBD-SKNVOMKLSA-N

BRENDA

ketogluconate metabolism

MetaCyc

ketogluconate metabolism, L-ascorbate degradation IV, L-idonate degradation

1.1.1.264

3 entries

1.1.1.366

L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+

761153, 670701, 743167

-

1.1.1.215

2 entries

1.1.1.272

2-dehydro-L-gulonic acid + NADPH + H+ = L-idonate + NADP+

0

-

1.1.1.366

5-dehydro-D-gluconate + NADH + H+ = L-idonate + NAD+

-

L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+

761153, 670701, 743167

-

1.1.1.411

L-idonate + NAD+ = L-sorbosonic acid + NADH + H+

762717

-

1.1.1.45

L-idonic acid + NAD+ = ?

-

5-dehydro-D-gluconate + NADH + H+ = L-idonate + NAD+

0

-

1.1.1.272

2-dehydro-L-gulonic acid + NADPH + H+ = L-idonate + NADP+

0

-

1.1.1.346

2-dehydro-L-gulonate + NADPH + H+ = L-idonate + NADP+

0

-

1.1.1.366

5-dehydro-D-gluconate + NADH + H+ = L-idonate + NAD+

0

-

1.1.1.215

1.1

-

pH 8, temperature not specified in the publication

5.5

-

pH 7.0, temperature not specified in the publication

12.6

-

pH 8, temperature not specified in the publication

30.9

-

pH 7.0, temperature not specified in the publication

5.3

-

cofactor NAD+, pH 8.5

286905

246372

9658018

Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonate acid catabolism in Escherichia coli

1998

Bausch, C.; Peekhaus, N.; Utz, C.; Blais, T.; Murray, E.; Lowary, T.; Conway, T.

J. Bacteriol.

180

3704-3710

285822

-

Distribution of 2-ketogluconate reductase and 5-ketogluconate reductase in acetic acid bacteria

1975

Chiyonobu, T.; Shinagawa, E.; Adachi, O.; Ameyama, M.

Agric. Biol. Chem.

39

2425-2427

285823

-

Crystallization and properties of 5-keto-D-gluconate reductase from Gluconobacter suboxydans

1979

Adachi, O.; Shinagawa, E.; Matsushita, K.; Ameyama, M.

Agric. Biol. Chem.

43

75-83

285824

-

A new enzyme, 5-ketoglucono-idono-reductase

1962

Takagi, Y.

Agric. Biol. Chem.

26

719-720

286273

-

Purification, crystallization and properties of 2-ketogluconate reductase from Acetobacter rancens

1976

Chiyonobu, T.; Shinagawa, E.; Adachi, O.; Ameyama, M.

Agric. Biol. Chem.

40

175-184

286274

-

Crystalline 2-ketogluconate reductase from Acetobacter ascendens, the second instance of crystalline enzyme in genus Acetobacter

1978

Adachi, O.; Chiyonobu, T.; Shinagawa, E.; Matsushita, K.; Ameyama, M.

Agric. Biol. Chem.

42

2057-2062

286275

-

2-keto-D-Gluconate reductase from acetic acid bacteria

1982

Ameyama, M.; Adachi, O.

Methods Enzymol.

89

203-210

286278

9501529

Purification and characterization of the 2-ketoaldonate reductase from Brevibacterium ketosoreductum ATCC21914

1998

Yum, D-Y.; Bae, S-S.; Pan, J-G.

Biosci. Biotechnol. Biochem.

62

154-156

286279

9811658

The yiaE gene, located at 80.1 minutes on the Escherichia coli chromosome, encodes a 2-ketoaldonate reductase

1998

Yum, D-Y.; Lee, B-Y.; Hahm, D-H.; Pan, J-G.

J. Bacteriol.

180

5984-5988

286905

-

Purification and properties of beta-L-hydroxy acid dehydrogenase

1961

Smiley, J.D.; Ashwell, G.

J. Biol. Chem.

236

357-364

286906

-

L-3-Aldonic acid dehydrogenase from Schwanniomyces occidentalis

1964

Dworsky, P.; Hoffmann-Ostenhof, O.

Acta Biochim. Pol.

9

269-277

670701

16567629

L-tartaric acid synthesis from vitamin C in higher plants

2006

DeBolt, S.; Cook, D.R.; Ford, C.M.

Proc. Natl. Acad. Sci. USA

103

5608-5613

741418

27189775

A novel pathway for fungal D-glucuronate catabolism contains an L-idonate forming 2-keto-L-gulonate reductase

2016

Kuivanen, J.; Sugai-Guerios, M.H.; Arvas, M.; Richard, P.

Sci. Rep.

6

26329

743167

25765362

Transcriptome comparison of Cabernet Sauvignon grape berries from two regions with distinct climate

2015

Sun, R.; He, F.; Lan, Y.; Xing, R.; Liu, R.; Pan, Q.; Wang, J.; Duan, C.

J. Plant Physiol.

178

43-54

761153

28261181

Clustered genes encoding 2-keto-L-gulonate reductase and L-idonate 5-dehydrogenase in the novel fungal D-glucuronic acid pathway

2017

Kuivanen, J.; Arvas, M.; Richard, P.

Front. Microbiol.

8

225

762717

32569553

Substrate diversity of L-threonic acid dehydrogenase homologs

2020

Zhang, C.F.; Liu, Y.P.; Wu, X.X.; Zhang, X.S.; Huang, H.

Biochemistry (Moscow)

85

463-471

Ligand L-idonic acid

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

Substrate in Enzyme-catalyzed Reactions (9 results)

Product in Enzyme-catalyzed Reactions (9 results)

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (6 results)

K_M Value (9 results)

References & Links

Literature References (16)

Links to other databases for L-idonic acid

Ligand L-idonic acid

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

Substrate in Enzyme-catalyzed Reactions (9 results)

Product in Enzyme-catalyzed Reactions (9 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

KM Value (9 results)

References & Links

Literature References (16)

Links to other databases for L-idonic acid

k_cat Value (Turnover Number) (6 results)

K_M Value (9 results)