Ligand (R)-adrenaline

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Basic Ligand Information

Molecular Structure
Picture of (R)-adrenaline (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H13NO3
(R)-adrenaline
UCTWMZQNUQWSLP-VIFPVBQESA-N
Synonyms:
(-)-Epinephrine, (R)-epinephrine, L-adrenalin, L-adrenaline, L-epinephrine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-adrenaline + NAD+ = ? + NADH + H+
show the reaction diagram
-
L-adrenaline + O2 = ?
show the reaction diagram
-
L-adrenaline + O2 = ?
show the reaction diagram
-
L-epinephrine + Fe2+ + O2 = ?
show the reaction diagram
-
2 S-adenosyl-L-methionine + (-)-epinephrine = 2 S-adenosyl-L-homocysteine + 4-O-methylepinephrine + 3-O-methylepinephrine
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
adrenalone + NADH + H+ = (R)-epinephrine + NAD+
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
requirement, agonist, alpha2-adrenergic receptor as substrate
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.00000148
-
pH 7.2, 20°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.455
-
pH 7.0, 40°C
0.0000239
-
pH 7.2, 20°C
13.7
-
-

References & Links

Links to other databases for (R)-adrenaline

ChEBI
PubChem
ChEBI
PubChem