Ligand ketopantoyl lactone

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Basic Ligand Information

Molecular Structure
Picture of ketopantoyl lactone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O3
ketopantoyl lactone
BJHIKXHVCXFQLS-LFRDXLMFSA-N
Synonyms:
2-dehydropantolactone, 2-Dehydropantonolactone, 2-Dehydropantoyl lactone, dihydro-4,4-dimethyl-2,3-furandione, oxopantoyl lactone
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydropantoyl lactone + NADPH = (R)-pantoyl lactone + NADP+
show the reaction diagram
-
2-dehydropantolactone + NADPH + H+ = (R)-pantolactone + NADP+
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dihydro-4,4-dimethyl-2,3-furandione + NADH + H+ = ?
show the reaction diagram
-
2-dehydropantolactone + NADPH + H+ = (R)-pantolactone + NADP+
show the reaction diagram
-
ketopantoyl lactone + NADPH + H+ = pantoyl lactone + NADP+
show the reaction diagram
-
ketopantoyl lactone + NADPH = NADP+ + ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive versus isatin
-
20 mM
-

Enzyme Kinetic Parameters

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
-
0.333
-
pH 7.0, 30°C
0.71
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.19
-
pH 7.0, 30°C, substrate: isatin

References & Links

Links to other databases for ketopantoyl lactone

ChEBI
PubChem
-
PubChem