Ligand Ethionine

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Basic Ligand Information

Molecular Structure
Picture of Ethionine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H13NO2S
Ethionine
GGLZPLKKBSSKCX-UHFFFAOYSA-N
Synonyms:
D,L-ethionine, DL-Ethionine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-vinylglycine + ethanethiol = ethionine
show the reaction diagram
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ethionyl-Ala + H2O = ethionine + Ala
show the reaction diagram
-
acetyl-DL-ethionine + H2O = acetate + DL-ethionine
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
enhances the activity of isozyme prolidase I, D,L-ethionine strongly enhances the activity of isozyme prolidase II compared with L-ethionine
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i.e. 2-amino-4-(ethylthio)butyric acid, an methionine analogue, which is converted to S-adenosyl-ethionine in vivo and activates CBS, treatment increased liver CBS activity 4.0fold in wild-type mice
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Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates at concentrations of 1-50 mM, overview
-
methionyl-tRNA formation
-

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.71
-
-

References & Links

Links to other databases for Ethionine

ChEBI
PubChem
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PubChem